ISSN 2097-6046（网络）
ISSN 2096-7446（印刷）
CN 10-1655/R
主管：中国科学技术协会
主办：中华护理学会
中华急危重症护理杂志

中华急危重症护理杂志 ›› 2026, Vol. 7 ›› Issue (5): 574-580.doi: 10.3761/j.issn.2096-7446.2026.05.010

• 急症护理研究 • 上一篇    下一篇

67例基孔肯雅热患者的临床特征观察及护理

黄少娟1(), 李淑芳1, 陈文元2, 陈星3, 梁艳桂3, 马晓军4, 黄清华4, 吴小堃1, 张改1, 陈苹5,*()   

  1. 1 广州中医药大学第八临床医学院/佛山市中医院护理部 广东省佛山市 528000
    2 广州中医药大学第八临床医学院/佛山市中医院院感科 广东省佛山市 528000
    3 广州中医药大学第八临床医学院/佛山市中医院医务科 广东省佛山市 528000
    4 广州中医药大学第八临床医学院/佛山市中医院感染科 广东省佛山市 528000
    5 广州中医药大学第八临床医学院/佛山市中医院院长办公室 广东省佛山市 528000
  • 收稿日期:2025-08-17 出版日期:2026-05-10 发布日期:2026-04-28
  • 通讯作者: *陈苹，E-mail：812264806@qq.com
  • 作者简介:黄少娟：女，硕士，主任护师，E-mail：863698794@qq.com
    第一联系人：

    黄少娟：核心概念、文献检索、数据采集、统计分析、文章准备、文章编辑、文章审查；李淑芳、陈文元：数据采集、数据分析、文章编辑；陈星、梁艳桂、马晓军、黄清华：数据采集；吴小堃，张改：文献检索、数据分析、文章准备、文章编辑；陈苹：核心概念、文章审查

  • 基金资助:
    广州中医药大学2025年护理“基础强化”项目——一级学科能力提升计划(GZY2025GB0923)

Clinical characteristics observation and nursing care of 67 patients with Chikungunya hemorrhagic fever

HUANG Shaojuan1(), LI Shufang1, CHEN Wenyuan2, CHEN Xing3, LIANG Yangui3, MA Xiaojun4, HUANG Qinghua4, WU Xiaokun1, ZHANG Gai1, CHEN Ping5,*()   

  1. 1 Department of Nursing， the Eighth School of Clinical Medicine，Guangzhou University of Chinese Medicine/Foshan Hospital of Traditional Chinese Medicine，Foshan， Guangdong Province 528000， China
    2 Department of Hospital Infection Control， the Eighth School of Clinical Medicine，Guangzhou University of Chinese Medicine/Foshan Hospital of Traditional Chinese Medicine，Foshan， Guangdong Province 528000， China
    3 Department of Medical Affairs， the Eighth School of Clinical Medicine，Guangzhou University of Chinese Medicine/Foshan Hospital of Traditional Chinese Medicine，Foshan， Guangdong Province 528000， China
    4 Department of Infectious Diseases， the Eighth School of Clinical Medicine，Guangzhou University of Chinese Medicine/Foshan Hospital of Traditional Chinese Medicine，Foshan， Guangdong Province 528000， China
    5 Director’s Office， the Eighth School of Clinical Medicine，Guangzhou University of Chinese Medicine/Foshan Hospital of Traditional Chinese Medicine，Foshan， Guangdong Province 528000， China
  • Received:2025-08-17 Online:2026-05-10 Published:2026-04-28
  • Contact: *CHEN Ping，E-mail：812264806@qq.com
  • Supported by:
    The Guangzhou University of Chinese Medicine 2025 Nursing “Foundation Strengthening”Program-First-Level Discipline Capability Enhancement Project(GZY2025GB0923)

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摘要：

目的 探讨67例基孔肯雅热患者的流行病学特征、临床特点与实验室检查变化，为临床护理实践提供参考。方法 采用回顾性研究方法，纳入2025年7月17日至8月5日广东省某三级甲等医院住院的67例基孔肯雅热患者为研究对象，收集并分析其人口学资料、流行病史、临床症状与体征、中医证型、基础疾病及实验室检测指标。结果 流行病学特征中，女43例（64.18%），男24例（35.82%），年龄14~85（49.19±18.28）岁，病例集中于7月下旬（62.69%）；临床特征以轻症为主（98.51%），主要临床表现为关节炎（86.57%）、皮疹（71.64%）、发热（67.16%）“三联征”；中医辨证以湿热蕴结证最常见（34.33%）；合并2种及以上基础疾病的患者占比26.87%，其中≥60岁以上老年患者占72.2%。实验室指标特征中，基孔肯雅热病毒核酸检测CT值为（28.27±7.59）；炎症指标（白细胞介素-6、C反应蛋白、肿瘤坏死因子）及D-二聚体普遍升高；肾小球滤过率、血清钾及白蛋白普遍降低。结论 2025年广东省基孔肯雅热疫情呈季节性聚集，以青壮年女性轻症患者多见，关节炎突出，伴炎症激活与代谢紊乱。提示在蚊媒传染病流行季节，护理人员预检分诊中应重视对高风险人群的早期识别，并基于中医证型与实验室检测指标，加强对炎症与凝血等异常指标的动态监测及个体化症状管理，以优化临床结局。

关键词: 基孔肯雅热, 临床特征, 护理, 回顾性研究

Abstract:

Objective To explore the epidemiological characteristics，clinical manifestations，and laboratory findings of patients with Chikungunya fever，and to offer evidence-based references for clinical nursing practice. Methods A retrospective analysis was performed on 67 hospitalized patients diagnosed with Chikungunya fever who were admitted to a tertiary grade A hospital between July 17 and August 5，2025. We collected and analyzed the data，including demographic features，epidemiological history，clinical symptoms and signs，traditional Chinese medicine （TCM） syndrome patterns，comorbidities，and laboratory findings. Results Among the 67 patients，43（64.18%） were female and 24（35.82%） were male，with an age range of 14-85 years（49.19 ± 18.28）. Cases were predominantly clustered in late July（62.69%）. The clinical characteristics are mainly mild（98.51%），with the main clinical mani-festations being the triad of arthritis（86.57%），rash（71.64%），and fever（67.16%）. The most common TCM syndrome pattern was damp-heat accumulation syndrome（34.33%）. Comorbidities（≥2 types） were present in 26.87% of patients，and 72.2% of these comorbid patients were aged ≥60 years. Laboratory findings showed that the CT value of the Chikungunya virus nucleic acid test was （28.27±7.59），markers（IL-6，CRP，TNF-α） and D-dimer levels were generally elevated，while the estimated glomerular filtration rate（eGFR），serum potassium，and albumin levels were commonly reduced. Conclusion The 2025 Chikungunya fever outbreak in Foshan，Guangdong Province，exhibited obvious seasonal clustering，with mild cases being more common in young and middle-aged females. Arthritis was a prominent clinical feature，accompanied by inflammatory activation and metabolic disturbances. During the endemic season of mosquito-borne diseases，nursing staff should prioritize the early identification of high-risk groups during pre-admission triage. Guided by TCM syndrome differentiation and laboratory findings，dynamic monitoring of inflammatory and coagulation markers should be strengthened，and individualized symptom management implemented to improve clinical outcomes.

Key words: Chikungunya Hemorrhagic Fever, Signs and Symptoms, Nursing Care, Retrospective Studies