ICU鲍曼不动杆菌研究热点的可视化分析

doi:10.3761/j.issn.2096-7446.2022.05.018

摘要/Abstract

摘要： 目的分析ICU鲍曼不动杆菌的研究热点及发展趋势。方法检索中国知网、Web of Science数据库建库至2022年1月收录的ICU鲍曼不动杆菌相关文献,运用CiteSpace 5.8.R3软件进行文献可视化分析。结果共纳入英文文献928篇,中文文献2 194篇,中文文献发文量从2008年之后呈现快速增长趋势,英文文献发文量从2014年后快速增长。聚类分析发现,中文文献形成ICU、重症肺炎、抗药性、细菌、耐药性、耐药率、感染、医院感染、危险因素、抗菌药物10个聚类,研究热点为替加环素、耐药基因及影响因素等;英文文献形成gene（基因）、colistin（粘菌素）、Gram negative bacteria（革兰氏阴性菌）、antimicrobial resistance（抗微生物药物耐药性）、Acinetobacter baumanii（鲍曼不动杆菌）、contamination（污染）、ventilator-associated pneumonia（呼吸机相关性肺炎）、antibiotic-resistance（抗生素耐药）、bacteria（细菌）9个聚类。研究热点为鲍曼不动杆菌感染的治疗与管理。高被引文献主要内容为鲍曼不动杆菌概念界定及其相关介绍。结论近年来关于ICU鲍曼不动杆菌相关文献数量持续增长,研究热点聚焦于对ICU鲍曼不动杆菌感染的流行病学调查、耐药机制、防控及护理措施的探讨。由于目前暂无鲍曼不动杆菌感染最佳治疗方案,未来可针对院感管理及防控措施开展更多护理研究。

关键词: 重症监护病房, 鲍氏不动杆菌, 交叉感染, 危重病护理, 文献计量学

Abstract: Objective To analyze the research hotspot and development trend of Acinetobacter baumannii in ICU. Methods The literatures related to Acinetobacter baumannii in ICU were retrieved from CNKI and Web of Science database until January 2022,and the literatures were visualized by CiteSpace 5.8.R3 software. Results A total of 928 English literatures and 2 194 Chinese literatures were included. The number of Chinese literatures showed a rapid growth trend from 2008,and the number of English literatures increased rapidly from 2014. Cluster analysis showed that clusters of ICU,severe pneumonia,drug resistance,bacteria,drug resistance,drug resistance rate,infection,nosocomial infection,risk factors and Antibacterial drugs were formed in Chinese literature,and the research hotspots were tegecycline,drug resistance genes and influencing factors. In English literature,gene,colistin,Gram negative bacteria,antimicrobial resistance,Acinetobacter baumanii,contamination,ventilator-associated pneumonia,antibiotic-resistance and bacteria were nine clusters. The research focus is the treatment and management of Acinetobacter baumannii infection. The main content of highly cited literature is the definition of Acinetobacter baumannii and its related introduction. Conclusion In recent years,the number of literature on Acinetobacter baumannii infection in ICU continues to increase,and the research focus is on the epidemiological investigation,drug resistance mechanism,prevention and control,and nursing measures of Acinetobacter baumannii infection in ICU. Since there is no optimal treatment plan for Acinetobacter baumannii infection at present,more nursing research can be carried out on the management and prevention and control measures of hospital infection in the future.

Key words: Intensive Care Units, Acinetobacter Baumannii, Cross Infection, Critical Care Nursing, Bibliometrics

李均凤, 唐帆, 沈锋, 吴柔, 罗尚荣. ICU鲍曼不动杆菌研究热点的可视化分析[J]. 中华急危重症护理杂志, 2022, 3(5): 468-472.

LI Junfeng, TANG Fan, SHEN Feng, WU Rou, LUO Shangrong. Clustering analysis on research hotspots of Acinetobacter baumannii in ICU[J]. Chinese Journal of Emergency and Critical Care Nursing, 2022, 3(5): 468-472.

参考文献

[1] Fan CY,Lee WT,Hsu TC,et al.Effect of chlorhexidine bath-ing on colonization or infection with Acinetobacter baumannii:a systematic review and meta-analysis[J]. J Hosp Infect,2019, 103(3):284-292.
[2] Garnacho-Montero J,Timsit JF.Managing Acinetobacter bauman-nii infections[J]. Curr Opin Infect Dis,2019,32(1):69-76.
[3] 汪静,何樱瑛,张颖华,等. 上海闵行区某医疗机构鲍曼不动杆菌污染分析[J]. 中国卫生检验杂志,2021,31(9):1120-1122, 1126.
Wang J,He YY,Zhang YH,et al.Analysis of Acinetobacter baumannii contamination in a medical institution in Minhang District[J]. Chin J Heal Lab Technol,2021,31(9):1120-1122, 1126.
[4] 毛劲松,朱莺莺,吴海燕,等. 从可视化分析看我国重症医学科多重耐药菌研究热点[J]. 中华危重病急救医学,2021(5):587-592.
Mao JS,Zhu YY,Wu HY,et al.Visual analysis of research on multidrug-resistant bacteria in intensive care unit in China[J]. Chin Crit Care Med,2021(5):587-592.
[5] 蒋钟吉,吴劲松,刘雪燕,等. 深圳某三甲医院2019年ICU病原菌分布及耐药性分析[J]. 中国抗生素杂志,2021,46(8):795-799.
Jiang ZJ,Wu JS,Liu XY,et al.Distribution and drug resistance of pathogens in ICU of a major hospital in Shenzhen in 2019[J]. Chin J Antibiot,2021,46(8):795-799.
[6] 胡付品,郭燕,朱德妹,等. 2018年CHINET中国细菌耐药性监测[J]. 中国感染与化疗杂志,2020,20(1):1-10.
Hu FP,Guo Y,Zhu DM,et al.CHINET surveillance of bacterial resistance in China:2018 report[J]. Chin J Infect Chemother,2020,20(1):1-10.
[7] Nasiri MJ,Zamani S,Fardsanei F,et al.Prevalence and mechanisms of carbapenem resistance in Acinetobacter baumannii:a comprehensive systematic review of cross-sectional studies from Iran[J]. Microb Drug Resist,2020,26(3):270-283.
[8] 陈安林,陈娅,陈泽慧,等. 医院感染多重耐药鲍曼不动杆菌患者死亡危险因素的Meta分析[J]. 中国感染控制杂志,2019,18(1):53-58.
Chen AL,Chen Y,Chen ZH,et al.Meta-analysis on risk factors for death in patients with healthcare-associated infection caused by multidrug-resistant Acinetobacter baumannii[J]. Chin J Infect Control,2019,18(1):53-58.
[9] 祝司霞,庞载元. 泛耐药鲍曼不动杆菌呼吸道定植如何管理?[J]. 中国全科医学,2019,22(27):3286-3291.
Zhu SX,Pang ZY.Management of extensively drug-resistant Aci-netobacter baumannii colonizes in the respiratory tract[J]. Chin Gen Pract,2019,22(27):3286-3291.
[10] 周华,周建英,俞云松. 中国鲍曼不动杆菌感染诊治与防控专家共识解读[J]. 中国循证医学杂志,2016,16(1):26-29.
Zhou H,Zhou JY,Yu YS.The interpretation of Chinese expert consensus for the diagnosis,treatment,prevention and control of acinetobacter baumannii infection[J]. Chin J Evid Based Med,2016,16(1):26-29.
[11] Magiorakos AP,Srinivasan A,Carey RB,et al.Multidrug-resistant,extensively drug-resistant and pandrug-resistant bacteria:an international expert proposal for interim standard definitions for acquired resistance[J]. Clin Microbiol Infect,2012, 18(3):268-281.
[12] Peleg AY,Seifert H,Paterson DL.Acinetobacter baumannii:emer-gence of a successful pathogen[J]. Clin Microbiol Rev,2008, 21(3):538-582.
[13] Horan TC,Andrus M,Dudeck MA.CDC/NHSN surveillance de-finition of health care-associated infection and criteria for specific types of infections in the acute care setting[J]. Am J Infect Control,2008,36(5):309-332.
[14] 陈悦,陈超美,刘则渊,等. CiteSpace知识图谱的方法论功能[J]. 科学学研究,2015,33(2):242-253.
Chen Y,Chen CM,Liu ZY,et al.The methodology function of CiteSpace mapping knowledge domains[J]. Stud Sci Sci,2015, 33(2):242-253.
[15] 胡付品,朱德妹,汪复,等. 2013年中国CHINET细菌耐药性监测[J]. 中国感染与化疗杂志,2014,14(5):365-374.
Hu FP,Zhu DM,Wang F,et al.CHINET 2013 surveillance of bacterial resistance in China[J]. Chin J Infect Chemother,2014,14(5):365-374.
[16] 陈佰义,何礼贤,胡必杰,等. 中国鲍曼不动杆菌感染诊治与防控专家共识[J]. 中国医药科学,2012,2(8):3-8.
Chen BY,He LX,Hu BJ,et al.Expert consensus on diagnosis,treatment and prevention and control of Acinetobacter baumannii infection in China[J]. China Med Pharm,2012,2(8):3-8.
[17] 孙世鹏,旷南岳,漆新文. 多重耐药鲍曼不动杆菌感染相关危险因素及耐药性分析[J]. 临床合理用药杂志,2018,11(1):7-8,11.
Sun SP,Kuang NY,Qi XW.Multiple drug resistant acinetobacter baumannii infection associated risk factors and drug resistance analysis[J]. Chin J Clin Ration Drug Use,2018,11(1):7-8,11.
[18] 王莉,张桂侠,卢晓娥. 某院重症医学科患者多重耐药鲍曼不动杆菌医院感染危险因素分析[J]. 中国消毒学杂志,2018,35(6):478-480.
Wang L,Zhang GX,Lu XE.Risk factors for nosocomial infection of multidrug-resistant Acinetobacter baumannii in a hospital[J]. Chin J Disinfect,2018,35(6):478-480.
[19] 胡旻昊,钱妙瑾,杨忠慧. ICU患者多重耐药鲍曼不动杆菌感染的危险因素及其耐药性分析[J]. 抗感染药学,2018,15(6):948-953.
Hu MH,Qian MJ,Yang ZH.Analysis on risk factors and drug resistance infected by multidrug-resistant acinetobacter baumannii in ICU patients[J]. Anti Infect Pharm,2018,15(6):948-953.
[20] 王瑞峰,曹大伟,张新日. 我国耐碳青霉烯类鲍曼不动杆菌医院感染危险因素的Meta分析[J]. 安徽医药,2020,24(11):2121-2127.
Wang RF,Cao DW,Zhang XR.A meta-analysis of risk factors for nosocomial infection of carbapenems resistant acinetobacter baumannii in China[J]. Anhui Med Pharm J,2020,24(11):2121-2127.
[21] 李娜,黄艳芳,唐喻莹,等. 多重耐药鲍曼不动杆菌医院感染危险因素荟萃分析[J]. 中国感染控制杂志,2017,16(2):115-120.
Li N,Huang YF,Tang YY,et al.Meta-analysis on risk factors for healthcare-associated infection with multidrug-resistant Acinetobacter baumannii[J]. Chin J Infect Control,2017,16(2):115-120.
[22] Ben-Chetrit E,Wiener-Well Y,Lesho E,et al.An intervention to control an ICU outbreak of carbapenem-resistant Acinetobacter baumannii:long-term impact for the ICU and hospital[J]. Crit Care,2018,22(1):319.
[23] 乔甫,宗志勇. 世界卫生组织《医疗机构耐碳青霉烯的肠杆菌科细菌、铜绿假单胞菌和鲍曼不动杆菌防控指南》介绍[J]. 华西医学,2018,33(3):259-263.
Qiao F,Zong ZY.Interpretation of guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae,acinetobacter baumannii and pseudomonas aeruginosa in health care facilities[J]. West China Med J,2018,33(3):259-263.
[24] 李阳洋,邵小平,蒋卓娟,等. ICU环境感染预防及管理的循证护理实践[J]. 中华急危重症护理杂志,2020,1(5):459-463.
Li YY,Shao XP,Jiang ZJ,et al.Evidence-based nursing practice for the prevention and management of environmental infection in ICU[J]. Chin J Emerg Crit Care Nurs,2020,1(5):459-463.
[25] 曾妃,封秀琴,赵锐祎,等. 群体大面积烧爆复合伤患者单元化感染防控的实践及成效[J]. 中华急危重症护理杂志,2021,2(2):123-126.
Zeng F,Feng XQ,Zhao RY,et al.The practice and effect of unit-based infection prevention and control in a group of patients with massive burn and explosion combined injury[J]. Chin J Emerg Crit Care Nurs,2021,2(2):123-126.
[26] 张燕红,胡静,顾莺,等. 危重症患儿机械通气下口腔护理频率的研究[J]. 中华急危重症护理杂志,2020,1(3):208-211.
Zhang YH,Hu J,Gu Y,et al.Research on the frequency of oral care in critical children with mechanical ventilation[J]. Chin J Emerg Crit Care Nurs,2020,1(3):208-211.