eISSN 2097-6046
ISSN 2096-7446
CN 10-1655/R
Responsible Institution:China Association for Science and Technology
Sponsor:Chinese Nursing Association

Chinese Journal of Emergency and Critical Care Nursing ›› 2026, Vol. 7 ›› Issue (6): 717-724.doi: 10.3761/j.issn.2096-7446.2026.06.015

• Quality and Safety • Previous Articles     Next Articles

Translation and validation of the Chinese version of the Newcastle Laryngeal Hypersensitivity Questionnaire

MEI Gaopeng(), LIU Jun, YANG Jianlan*()   

  1. Emergency and Critical Care Medicine DepartmentAffiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou 215000, China
  • Received:2025-07-24 Online:2026-06-10 Published:2026-06-02
  • Contact: YANG Jianlan E-mail:meigp93@163.com;mjianmei77@126.com

Abstract:

Objective To translate the Newcastle Laryngeal Hypersensitivity Questionnaire(NLHQ) into Chinese and validate the reliability and validity of the Chinese version of the NLHQ scale in critically ill mechanically ventilated patients. Methods After obtaining permission from the original author,the NLHQ was translated using the Brislin translation model. A total of 285 critically ill mechanically ventilated patients admitted to a tertiary hospital in Suzhou between July 2023 and January 2025 were selected to validate the reliability and validity of the questionnaire. Results The Chinese version of the NLHQ scale consisted of 3 dimensions and 13 items. The Cronbach’s α coefficient was 0.853,the split-half reliability was 0.827,and the content validity index (S-CVI/Ave) was 0.973. Exploratory factor analysis extracted 3 common factors,with a cumulative variance contribution rate of 67.67%. Confirmatory factor analysis showed good model fit. Criterion validity indicated that the Chinese version of the NLHQ scale score was negatively correlated with the Chinese version of the Hull Airway Reflux Questionnaire (HARQ) scale score(r<0,P<0.05). The ROC curve analysis revealed that the AUC of the NLHQ score for predicting extubation failure in critically ill mechanically ventilated patients was 0.895(95%CI:0.844-0.946),with an optimal cutoff value of 39 points. Conclusion The Chinese version of the NLHQ scale demonstrates good reliability and validity and can be used as a tool to assess laryngeal discomfort in critically ill mechanically ventilated patients in China. It also has certain predictive value for extubation failure.

Key words: Newcastle Laryngeal Hypersensitivity Questionnaire, Critical Mechanical Ventilation, Sinification, Reliability, Validity