Objective To develop an expert consensus on the prevention and nursing care of postoperative delirium in adults(hereinafter referred to as the“consensus”),to guide the nursing of postoperative delirium in adults. Methods The guidelines,expert consensuses,systematic reviews,and original studies related to postoperative delirium in adults were searched in domestic and international databases and related websites,with the search period from the establishment of the database to May 2024. The first draft of the consensus was written through literature review,stakeholder interviews and expert meeting. From December 2024 to January 2025,19 experts were invited to conduct two rounds of letter consultation,revise and improve the content of the first draft,determine the level of evidence and recommendation strength,and form the final draft of the consensus. Results The content of the “consensus” includes five aspects:classification,risk factors,assessment and identification,prevention,and nursing care of postoperative delirium in adults. Conclusion This consensus can provide practical guidance for clinical nursing staff in the prevention and nursing care of postoperative delirium in adults.