不同体温状态对脓毒症患者预后影响的Meta分析

doi:10.3761/j.issn.2096-7446.2025.05.020

Abstract

Abstract:

Objective To investigate the effect of body temperature on prognosis in septic patients. Methods PubMed，Embase，the Cochrane Library，Web of Science，China Biomedical Literature Database，Wanfang Data Knowledge Service Platform，China National Knowledge Infrastructure，VIP database were electronically searched to collect case-control studies，prospective or retrospective cohort studies on the effect of body temperature on the prognosis of septic patients from inception of database to June 1，2024. Two reviewers performed independent literature screening，data extraction，and evaluating the risk of bias in the included studies，then performed meta-analysis by RevMan 5.4.1 software. Results 23 articles were included，with a total of 3 516 745 patients. The results showed that fever and hypothermia had significant effects on hospital mortality and 28d mortality（P<0.01），and the impact on the length of hospitalization and ICU stay was not yet clear（P>0.05）. Conclusion This meta-analysis showed that fever and hypothermia can increase the hospital mortality and 28d mortality in patients with sepsis. Therefore，during the process of clinical diagnosis and treatment and nursing，it is necessary to closely observe the change of body temperature，take the corresponding body temperature control strategies in time，and improve patient’s outcome.

Key words: Body Temperature, Sepsis, Prognosis, Meta-analysis

LI Ji, JIN Jingfen, ZHANG Yuping, CHENG Yifeng, WANG Xuyang. Effect of different body temperature on prognosis in septic patients：a meta-analysis[J]. Chinese Journal of Emergency and Critical Care Nursing, 2025, 6(5): 616-623.

Figures/Tables 5

References 33

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Effect of different body temperature on prognosis in septic patients：a meta-analysis

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