Abstract:

Objective To conduct a meta-analysis to understand the prehospital delay rate and influencing factors in patients with acute myocardial infarction. Methods Literature related to the prehospital delay rates and risk factors in patients with acute myocardial infarction was retrieved from CNKI，VIP，Wanfang，China Biomedical Literature Database，PubMed，Cochrane Library，Embase，and Web of Science databases. The search time limit was from establishing the database to March 2024. Analysis was performed using Rev Man 5.4 and Stata 18.0. Results A total of 20 articles were included，involving 49 041 patients with acute myocardial infarction. The occurrence rates of prehospital delays were 61%（95%CI：53%-69%） at 2 hours，58%（95%CI：43%-72%） at 3 hours，and 40%（95%CI：30%-50%） at 6 hours. Factors influencing prehospital delay included sociodemographic factors included educational level（OR=1.50），age（OR=1.58），gender（OR=0.68），living alone（OR=2.40），and place of residence（OR=2.24）；disease-related factors were history of diabetes（OR=1.54），atypical symptoms（OR=1.42），history of coronary heart disease（OR=1.72）；and other factors included mode of admission（OR=0.49），onset during the day（OR=0.62），symptom attri-bution（OR=4.97）. Conclusion The prehospital delay rate of patients with acute myocardial infarction is high，and factors affecting it cover various aspects such as sociodemographic and disease-related factors. Further research is needed to explore the relationship between influencing factors and prehospital delay to effectively reduce the occurrence of prehospital delay in patients with acute myocardial infarction.

Key words: Acute Myocardial Infarction, Prehospital Delay, Risk Factors, Meta-analysis