目标体温管理在心搏骤停患者中应用效果的系统评价再评价

doi:10.3761/j.issn.2096-7446.2025.02.008

Abstract

Abstract:

Objective To summarize，evaluate and analyze the related systematic reviews/meta-analyses of the application of targeted temperature management（TTM） in patients with cardiac arrest（CA），so as to provide evidence support for clinical medical staff. Methods CNKI，Wanfang，VIP，CBM，PubMed，Embase，Web of Science，Cochrane Library and CINAHL databases were searched by computer. Systematic reviews/meta-analyses evaluating the application effect of TTM in patients with CA were included. The search time limit was from the establishment of the database to January 15，2024. Two researchers independently screened the literature and extracted the data，assessed the extent of original study overlap by calculating Corrected Covered Area（CCA）. AMSTAR 2 tool，PRISMA 2020 reporting standard and GRADE evidence grading system were used to evaluate the methodology，reporting and evidence quality of the included studies，respectively. Descriptive analysis was used to present the results. Results A total of 23 systematic reviews/meta-analyses were included. The original studies were highly overlapping by calculating a CCA of 10.32%. The results of AMSTAR 2 evaluation showed that 2 articles were of high quality，2 articles were of medium quality，8 articles were of low quality and 11 articles were of very low quality. The results of PRISMA 2020 evaluation showed that 12 reports were relatively complete，and 11 reports had certain defects. The GRADE evaluation results showed that 8 of the 55 evidence bodies were medium quality，25 were low quality，and 22 were very low quality.The results of descriptive analysis showed that TTM has potential benefits for CA patients in terms of improving neurological function recovery，improving survival rate，reducing mortality and improving quality of life，but its effects on cost-effectiveness and length of hospital stay need to be further confirmed. Conclusion TTM has potential benefits in improving neurological recovery and survival，decreasing their death rate and improving their quality of life in CA patients，but the optimal body temperature has not yet been clarified and the quality of related systematic reviews/meta-analyses needs to be improved. Future scholars should aim to explore personalized treatment strategies and improve the level of knowledge and practice of TTM among clinical nurses，so as to ensure the effectiveness of TTM treatment and improve the prognosis of CA patients.

Key words: Targeted Temperature Management, Cardiac Arrest, Application Effect, Overview of Systematic Reviews, Nursing Care

LI Xin, LI Zhangshuangzi, CUI Anni, XU Aoran, HAN Yaxian. Effectiveness of targeted temperature management in patients with cardiac arrest：an overview of systematic reviews[J]. Chinese Journal of Emergency and Critical Care Nursing, 2025, 6(2): 173-180.

Figures/Tables 1

References 37

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Effectiveness of targeted temperature management in patients with cardiac arrest：an overview of systematic reviews

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