脓毒症患者ICU获得性肌无力早期康复的研究进展

doi:10.3761/j.issn.2096-7446.2022.04.006

Abstract

Abstract: The incidence of intensive care unit acquired weakness（ICU-AW） in sepsis patients is as high as 50%~100%,which is an important factor affecting the prognosis of sepsis. Early rehabilitation is an important means to prevention and treatment of ICU-AW in sepsis patients. This paper reviews the significance,assessment,practice and evaluation indexes of early rehabilitation in ICU-AW prevention and treatment among sepsis patients,aiming at improving the awareness of physicians and nurses to prevent ICU-AW in sepsis patients,promoting the implementation of early rehabilitation practice,so as to improve the outcomes of sepsis patients and help them live with quality.

Key words: Sepsis, ICU-acquired Weakness, Early Rehabilitation, Critical Care Nursing, Rehabilitation Nursing

CHEN Huiyao, LI Xingsong, ZHANG Li. The early rehabilitation of ICU acquired weakness in sepsis patients：a review[J]. Chinese Journal of Emergency and Critical Care Nursing, 2022, 3(4): 326-330.

References

[1] Evans L,Rhodes A,Alhazzani W,et al.Surviving sepsis campaign:international guidelines for management of sepsis and septic shock 2021[J]. Intensive Care Med,2021,47(11):1181-1247.
[2] Fan E,Cheek F,Chlan L,et al.An official American Thoracic Society Clinical Practice guideline:the diagnosis of intensive care unit-acquired weakness in adults[J]. Am J Respir Crit Care Med,2014,190(12):1437-1446.
[3] Latronico N,Bolton CF.Critical illness polyneuropathy and myopathy:a major cause of muscle weakness and paralysis[J]. Lancet Neurol,2011,10(10):931-941.
[4] 胡燕,胡晓莹,肖伽,等. 早期活动对ICU患者身体功能状态影响的Meta分析[J]. 中华危重病急救医学,2019(4):458-463.
Hu Y,Hu XY,Xiao J,et al.Effect of early mobilization on the physical function of patients in intensive care unit:a Meta-analysis[J]. Chin Crit Care Med,2019(4):458-463.
[5] Sossdorf M,Otto GP,Menge K,et al.Potential effect of physiotherapeutic treatment on mortality rate in patients with severe sepsis and septic shock:a retrospective cohort analysis[J]. J Crit Care,2013,28(6):954-958.
[6] Kayambu G,Boots R,Paratz J.Early physical rehabilitation in intensive care patients with sepsis syndromes:a pilot randomised controlled trial[J]. Intensive Care Med,2015,41(5):865-874.
[7] 魏丽丽,韩斌如. 以护士为主导的早期活动方案在机械通气患者中的应用研究[J]. 中华护理杂志,2019,54(12):1765-1770.
Wei LL,Han BR.Application of nurse-led early activity procedure in patients with mechanical ventilation[J]. Chin J Nurs,2019,54(12):1765-1770.
[8] 王敏,曾妃,郑叶平. 重症体外膜肺氧合患者早期肺康复训练的护理[J]. 中华急危重症护理杂志,2020,1(5):436-438.
Wang M,Zeng F,Zheng YP.Nursing care of early pulmonary rehabilitation training for severe patients with extracorporeal membrane oxygenation[J]. Chin J Emerg Crit Care Nurs,2020, 1(5):436-438.
[9] 周极新,朱菱,谢湘梅. 以护士为主导的早期肺康复治疗在预防呼吸机相关膈肌功能障碍中的效果观察[J]. 全科护理,2021, 19(23):3220-3224.
Zhou JX,Zhu L,Xie XM.Observation of the effect of nurse-led early pulmonary rehabilitation therapy in the prevention of ventilator-associated diaphragmatic dysfunction[J]. Chin Gen Pract Nurs,2021,19(23):3220-3224.
[10] 朱云龙,袁光雄,许俊,等. 早期康复训练对严重脓毒症患者ICU获得性肌无力的影响[J]. 内科急危重症杂志,2016,22(1):43-45.
Zhu YL,Yuan GX,Xu J,et al.Early rehabilitation training on patients with severe sepsis acquired muscle weakness in the ICU[J]. J Crit Care Intern Med,2016,22(1):43-45.
[11] Hickmann CE,Castanares-Zapatero D,Deldicque L,et al.Impact of very early physical therapy during septic shock on skeletal muscle:a randomized controlled trial[J]. Crit Care Med, 2018,46(9):1436-1443.
[12] Hodgson CL,Schaller SJ,Nydahl P,et al.Ten strategies to optimize early mobilization and rehabilitation in intensive care[J]. Crit Care,2021,25(1):324.
[13] Aquim EE,Bernardo WM,Buzzini RF,et al.Brazilian guidelines for early mobilization in intensive care unit[J]. Revista Brasileira de Terapia Intensiva,2019,31(4):434-443.
[14] Devlin JW,Skrobik Y,et al.Clinical practice guidelines for the prevention and management of pain,agitation/sedation,delirium,immobility,and sleep disruption in adult patients in the ICU[J]. Crit Care Med,2018,46(9):e825-e873.
[15] 杨睿琦,甘秀妮,等. ICU机械通气病人早期主动活动安全评估量表的构建[J]. 护理研究,2022,36(5):807-814.
Yang RQ,Gan XN,et al.Development of the safety assessment scale for early active mobilization of ICU mechanically ventilated patients[J]. Chin Nurs Res,2022,36(5):807-814.
[16] 武亮,郭琪,胡菱,等. 中国呼吸重症康复治疗技术专家共识[J]. 中国老年保健医学,2018,16(5):3-11.
Wu L,Guo Q,Hu L,et al.Chinese respiratory critical illness rehabilitation treatment technical experts consensus[J]. Chin J Geriatr Care,2018,16(5):3-11.
[17] Hodgson CL,Stiller K,Needham DM,et al.Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults[J]. Crit Care,2014,18(6):658.
[18] 韩汝宁,李秀川,赵士兵,等. ICU患者早期康复方案的构建及应用研究[J]. 中华护理杂志,2020,55(1):8-15.
Han RN,Li XC,Zhao SB,et al.Construction and application of early rehabilitation scheme for intensive care unit patients[J]. Chin J Nurs,2020,55(1):8-15.
[19] 戈蕊,姚彦蓉,刘娜,等. 机械通气病人ICU获得性衰弱风险评估指标的构建[J]. 循证护理,2020,6(4):308-312.
Ge R,Yao YR,Liu N,et al.Construction of risk assessment index of ICU-acquired weakness among patients with mechanical ventilation[J]. Chin Evid Based Nurs,2020,6(4):308-312.
[20] 王秋雁,边仁秀,戎军,等. 浙江省重症康复专家共识[J]. 浙江医学,2017,39(24):2191-2196,2209.
Wang QY,Bian RX,Rong J,et al.Zhejiang Province severe rehabilitation expert consensus[J]. Zhejiang Med J,2017,39(24):2191-2196,2209.
[21] 莫韶妹,冼燕珊,李绮慈,等. 改良呼吸操在COPD机械通气患者中的应用研究[J]. 护理学报,2014,21(13):20-22.
Mo SM,Xian YS,Li QC,et al.Application of modified respiratory exercises in COPD[J]. J Nurs,2014,21(13):20-22.
[22] 谌绍林,蒋玉兰,禹斌,等. 经皮神经肌肉电刺激对COPD机械通气患者ICU-AW的预防效果[J]. 中华危重病急救医学,2019,31(6):709-713.
Shen SL,Jiang YL,Yu B,et al.Effect of transcutaneous neuromuscular electrical stimulation on prevention of intensive care unit-acquired weakness in chronic obstructive pulmonary disease patients with mechanical ventilation[J]. Chin Crit Care Med,2019,31(6):709-713.
[23] 许卓谦,叶家骏,姚淑雯,等. 早期神经肌肉电刺激在脓毒症机械通气患者治疗中的效果[J]. 中国当代医药,2019,26(18):55-57.
Xu ZQ,Ye JJ,Yao SW,et al.Effect of early neuromuscular electrical stimulation in the treatment of sepsis patients with mechanical ventilation[J]. China Mod Med,2019,26(18):55-57.
[24] Waldauf P,Gojda J,Urban T,et al.Functional electrical stimulation-assisted cycle ergometry in the critically ill:protocol for a randomized controlled trial[J]. Trials,2019,20(1):724.
[25] 宋伟,王明明,凌受毅,等. 床旁膈肌超声评价电针预防脓毒症患者获得性肌无力的效果[J]. 临床超声医学杂志,2021,23(5):355-359.
Song W,Wang MM,Ling SY,et al.Effect of electro-acupuncture on acquired weakness in sepsis patients evaluated by bedside diaphragmatic ultrasound[J]. J Clin Ultrasound Med,2021,23(5):355-359.
[26] 梁冰,张莉,张可,等. 早期中西医结合集束化干预策略对预防ICU获得性衰弱的研究[J]. 中国实用护理杂志,2020,36(13):979-983.
Liang B,Zhang L,Zhang K,et al.Study on early integrated Chinese and western medicine cluster intervention strategy in preventing intensive care unit acquired weakness[J]. Chin J Pract Nurs,2020,36(13):979-983.
[27] Chen WT,Sun C,Zhou YB,et al.Evaluation on the effect of acupuncture on patients with sepsis-induced myopathy(ACU-SIM pilot study):a single center,propensity-score stratified,assessor-blinded,prospective pragmatic controlled trial[J]. Me-dicine(Baltimore),2020,99(21):e20233.

The early rehabilitation of ICU acquired weakness in sepsis patients：a review

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	GUO Miao, YANG Yanjun, QIAO Li, YANG Tingting, ZHANG Ping. Study on the impact of humanistic care nursing based on the peak-end rule on satisfaction of ICU patients and their families [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(7): 773-779.
[2]	YANG Li, XU Xiaobin, WANG Huafen. Application progress of functional near-infrared spectroscopy in critical care nursing [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(7): 836-840.
[3]	ZHANG Yixiang, LÜ Wei, HE Cuili, LIU Liping, NONG Kang, XIE Fangna. Rapid identification and nursing for 109 patients with botulinum toxin type A injection-induced poisoning [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(7): 846-848.
[4]	LIU Xiaoting, WANG Ping, XU Yihong, FAN Tingting, FU Zhenzhen, XIONG Zihan, HE Beilei, CHEN Xiaohui, ZHANG Xiaoming, SHU Yan. Nursing care for a patient with ultra-short bowel syndrome and multiple stomas after surgery for allied disorders of Hirschsprung’s disease [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(7): 849-851.
[5]	SHAO Lihong, LI Chunyan, DONG Xiaoqi, WANG Qiaolin, YE Guofeng, ZHAO Qiaomei. Nursing care for multiple severe complications after free flap transplantation in a patient with oral multiple primary cancer [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(7): 852-855.
[6]	PAN Chenxin, ZHANG Yan, LI Xihan, CHEN Jing. Summary of the best evidence for the application of the family participation model in the rehabilitation nursing of ICU patients [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(7): 870-876.
[7]	ZHANG Hui, HE Xuehua, WANG Li, GONG Xiaoyan, ZHUANG Yiyu. Early warning and nursing intervention for primary graft dysfunction after heart transplantation using a marginal donor heart：a case report [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 682-684.
[8]	ZENG Fei. Nursing care of a patient with familial hypertrophic cardiomyopathy complicated with liver failure undergoing simultaneous heart-liver transplantation [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 685-688.
[9]	YANG Muying, FAN Wenqi, HU Han. Early identification and emergency nursing of cerebral hemorrhage during dialysis in a maintenance hemodialysis patient [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 704-706.
[10]	ZHUANG Jiani, LI Xiaozhen, SHI Chaoqiang, WANG Ying, TAN Liping. Perioperative nursing care for a patient with malignant mediastinal abscess secondary to deep neck infection [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 707-709.
[11]	LI Gaile, PAN Wenyan, LI Jingjing, LIU Xiao, TANG Yingjia, HOU Jin. Nursing care of a post-liver transplantation patient complicated with pneumocystis jirovecii and cytome-galovirus infection [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 710-713.
[12]	WANG Yan, LU Fangyan, LIU Yuan, WANG Fang. Postoperative care of children with progressive familial intrahepatic cholestasis undergoing parental liver transplantation [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 714-716.
[13]	CAI Shasha, SHUAI Qinyan, HE Yangmengyuan, ZHANG Mei, XIANG Xinyue, ZHANG Mingyue, HUANG Lihua. Evidence summary for the management of mechanical ventilation in patients with sepsis [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(6): 740-747.
[14]	LI Zunzhu, CHANG Xiaowei, CAO Qianqian, ZHAO Mingxi, LUO Hongbo, JING Jie, SUN Jianhua, LAN Yuanmei, WU Xinjuan. The construction and applicability analysis of a respiratory rehabilitation management program for the early postoperative period in patients undergoing cardiopulmonary bypass cardiac surgery [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(5): 532-539.
[15]	YU Xiangling, ZHAO Xiaoyan, CHEN Fan, LIN Yumin, DENG Sufen, HUANG Yufeng. Nursing care of a premature infant with difficulty in catheterization and PICC catheter placement via thoracoepigastric vein [J]. Chinese Journal of Emergency and Critical Care Nursing, 2026, 7(5): 561-563.