Abstract:

Objective To investigate the rate and influencing factors of in-hospital door-to-balloon time delay in patients with acute ST-segment elevation myocardial infarction（STEMI）. Methods PubMed，Cochrane Library，Web of Science，Embase，CBM，CNKI，Wan Fang and VIP were systematically searched for related literature on the rate and influencing factors of in-hospital door-to-balloon time delay in patients with acute ST-segment elevation myocardial infarction，the search period was from the establishment of the databases until July 31，2025. Meta-an-alysis was performed using Stata 18.0 and RevMan 5.4. Results A total of 20 studies were included. The meta-analysis results showed that the in-hospital door-to-balloon time delay rate was 42%. The identified risk factors included rural residence（OR=3.12），non-ambulance admission（OR=2.52），presentation on non-working days（OR=2.15），history of gastrointestinal diseases（OR=2.79），female（OR=1.41），advanced age（OR=1.39），self-payment（OR=1.07），history of diabetes（OR=1.17），history of renal diseases（OR=1.64），history of peripheral vascular diseases（OR=1.22） and higher education level（OR=0.39）. Conclusion The in-hospital door-to-balloon delay rate in STEMI patients is relatively high and affected by multiple factors. For these high-risk populations，healthcare providers should conduct structured screening，prioritize triage protocols and establish a 24-hour on-call system for the interventional team. Meanwhile，multidisciplinary collaboration processes in chest pain centers should be systematically optimized，and the construction of chest pain referral networks in rural areas should be improved. This study provides an evidence-based basis for developing individualized intervention strategies and achieving the guideline-recommended goal of door-to-balloon delay≤90 minutes.

Key words: Acute Myocardial Infarction, In-Hospital Delay, Door To Balloon Time, Meta-Analysis, Evidence-Based Nursing