eISSN 2097-6046
ISSN 2096-7446
CN 10-1655/R
Responsible Institution:China Association for Science and Technology
Sponsor:Chinese Nursing Association

Chinese Journal of Emergency and Critical Care Nursing ›› 2026, Vol. 7 ›› Issue (4): 404-411.doi: 10.3761/j.issn.2096-7446.2026.04.003

• Research Paper • Previous Articles     Next Articles

Latent profile analysis of symptom burden in patients with acute coronary syndrome after percutaneous coronary intervention

HONG Shuqin(), GAN Xiuni*(), ZHOU Wen, LIU Li, GAO Yan   

  1. Department of Nursingthe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010, China
  • Received:2025-11-26 Online:2026-04-10 Published:2026-04-02
  • Contact: GAN Xiuni E-mail:hsq032611@163.com;300650@cqmu.edu.cn

Abstract:

Objective To identify latent profiles of symptom burden in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention(PCI) and to explore factors associated with different profiles,so as to provide evidence for stratified nursing management. Methods A convenience sampling method was used to recruit 261 patients with ACS who underwent PCI at a tertiary hospital in Chongqing,China,between November 2024 and August 2025. Data were collected using a general information questionnaire,the Cardiac Symptom Survey,and the Seattle Angina Questionnaire. Latent profile analysis was conducted to identify latent classes of symptom burden,and multinomial logistic regression analysis was performed to examine factors associated with different profiles. Results Three latent profiles of symptom burden after PCI were identified,including low symptom burden(62.8%),ischemic symptom dominant type(18.4%),and cardiopulmonary symptom dominant type(18.8%). Multinomial logistic regression analysis indicated that age(≥65 years) and multiple stent implantation(≥2) were significantly associated with the cardiopulmonary symptom-dominant profile(P<0.05),whereas female was independently associated with the ischemic symptom dominant profile(OR=2.453,P<0.05). Conclusion Symptom burden after PCI in patients with ACS shows marked heterogeneity. In clinical nursing practice,high-risk patients should be identified based on symptom profile characteristics,and stratified management and targeted interventions should be implemented.

Key words: Acute Coronary Syndrome, Percutaneous Coronary Intervention, Symptom Burden, Latent Profile Analysis, Nursing