Abstract:

Objective To explore the epidemiological characteristics，clinical manifestations，and laboratory findings of patients with Chikungunya fever，and to offer evidence-based references for clinical nursing practice. Methods A retrospective analysis was performed on 67 hospitalized patients diagnosed with Chikungunya fever who were admitted to a tertiary grade A hospital between July 17 and August 5，2025. We collected and analyzed the data，including demographic features，epidemiological history，clinical symptoms and signs，traditional Chinese medicine （TCM） syndrome patterns，comorbidities，and laboratory findings. Results Among the 67 patients，43（64.18%） were female and 24（35.82%） were male，with an age range of 14-85 years（49.19 ± 18.28）. Cases were predominantly clustered in late July（62.69%）. The clinical characteristics are mainly mild（98.51%），with the main clinical mani-festations being the triad of arthritis（86.57%），rash（71.64%），and fever（67.16%）. The most common TCM syndrome pattern was damp-heat accumulation syndrome（34.33%）. Comorbidities（≥2 types） were present in 26.87% of patients，and 72.2% of these comorbid patients were aged ≥60 years. Laboratory findings showed that the CT value of the Chikungunya virus nucleic acid test was （28.27±7.59），markers（IL-6，CRP，TNF-α） and D-dimer levels were generally elevated，while the estimated glomerular filtration rate（eGFR），serum potassium，and albumin levels were commonly reduced. Conclusion The 2025 Chikungunya fever outbreak in Foshan，Guangdong Province，exhibited obvious seasonal clustering，with mild cases being more common in young and middle-aged females. Arthritis was a prominent clinical feature，accompanied by inflammatory activation and metabolic disturbances. During the endemic season of mosquito-borne diseases，nursing staff should prioritize the early identification of high-risk groups during pre-admission triage. Guided by TCM syndrome differentiation and laboratory findings，dynamic monitoring of inflammatory and coagulation markers should be strengthened，and individualized symptom management implemented to improve clinical outcomes.

Key words: Chikungunya Hemorrhagic Fever, Signs and Symptoms, Nursing Care, Retrospective Studies