Abstract: Objective To construct a simulation course of opioid-induced clinical crisis management for pain nurse in ward and evaluate its effects. Methods Following the best practice standards of International Nursing Association for Clinical Simulation and Learning,according to the five basic dimensions of scenario development,facilitator preparation,equipment preparation,environmental preparation and pre-course student preparation,a opioid-induced clinical crisis management simulation course was constructed. From November to December 2019,a group of 61 pain nurses in wards from a tertiary general hospital in Zhejiang Province were selected for training in the simulation teaching center of the Anesthesia-Operation Department of the hospital. The teaching evaluation was carried out by using the questionnaire of Critical Thinking Disposition Inventory and clinical decision-making self-confidence assessment of excessive sedation and respiratory depression caused by opioids. Results After training,the total score of critical thinking was （264.57± 2.77）. There were statistical differences before and after the training（P< 0.05）. After training,the clinical decision-making self-confidence of the trainees in the excessive sedation and respiratory depression caused by opioids was（3.89± 0.82） and（3.89± 0.80） respectively,which were statistically different compared with those before the training（P< 0.001）. Pain nurses in wards were highly satisfied with the simulation teaching course. Conclusion The simulation course can effectively improve the clinical crisis management ability and clinical decision-making confidence of pain nurses in wards,and can provide reference for the training of comprehensive emergency response ability of pain nurses.

Key words: Nurse, Pain Management, Analgesics,Opioid, Clinical Crisis Management, Analog Simulation, Curriculum