Abstract:

Objective To systematically summarize the relevant evidence of post-extubation oxygen therapy methods for mechanically ventilated patients，so as to construct a flow chart of oxygen therapy methods based on the best evidence，for providing the reference for clinical staff to make oxygen therapy decisions. Methods We systematically searched the literature on the post-extubation oxygen therapy methods for mechanically ventilated patients in guideline websites and databases（inception of the database to January 12，2024）. The literature was evaluated according to the corresponding evaluation criteria，and the evidence was extracted and integrated. Results A total of 13 literature incorporated，including three clinical decisions，five guidelines，an evidence summary，an expert consensus，a systematic review，and two randomized controlled trials. The 24 pieces of best evidence were summarized from 4 aspects，including basic principles，application indications，application methods，precautions. The post-extubation oxygen therapy flow chart for mechanically ventilated patients was constructed. Conclusion This study summarized the best evidence of post-extubation oxygen therapy for mechanically ventilated patients and constructed the flow chart of oxygen therapy，which can provide a basis for clinical standardized selection of post-extubation oxygen therapy methods.

Key words: Ventilators, Mechanical, Extubation, Oxygen Therapy, Flow Chart, Evidence-Based Nursing