eISSN 2097-6046
ISSN 2096-7446
CN 10-1655/R
Responsible Institution:China Association for Science and Technology
Sponsor:Chinese Nursing Association

Chinese Journal of Emergency and Critical Care Nursing ›› 2024, Vol. 5 ›› Issue (12): 1123-1129.doi: 10.3761/j.issn.2096-7446.2024.12.012

• Evidence Synthesis Research • Previous Articles     Next Articles

The impact of nurse-led programmatic weaning protocol on mechanical ventilation outcomes in ICU patients:a systematic review

BASANG Kangzhuo, SUN Jianhua, LUO Hongbo, LI Zunzhu, LUOSANG Danzeng, JING Jie, ZHAO Mingxi, XIE Lingli, JIANG Miao   

  • Received:2023-12-13 Published:2024-12-10

Abstract: Objective To evaluate the effectiveness and safety of nurse-led programmatic weaning protocol on mechanical ventilation outcomes in Intensive Care Unit,so as to provide reference for early standardized weaning of mechanical ventilation. Methods PubMed,Embase,Cochrane Library,Web of Science,China National Knowledge Infrastructure,WanFang Database,China Biomedical Literature Database,and VIP Database were retrieved. The search deadline was from database establishment to August 5,2023. Two researchers independently selected literature,extracted data,and evaluated the quality of the literature. RevMan 5.3 was used for meta-analysis. Results 9 randomized controlled trials were included. Meta-analysis showed that nurse-led programmatic ventilator weaning protocol could shorten mechanical ventilation time [MD=-37.05,95%CI(-57.93,-16.16),P=0.005] and reduce ICU hospitalization time[MD=-5.58,95%CI(-9.91,-1.24),P=0.010],with statistically significant differences. However,there was no statistically significant difference in patient mortality[OR=0.99,95%CI(0.70,1.42),P=0.9]. Conclusion The nurse-led programmatic ventilator weaning protocol is safe and effective,which helps to shorten mechanical ventilation time,reduce ICU hospitalization time,and provides evidence for the nursing practice of mechanical ventilation for ICU patients.

Key words: Intensive Care Units, Ventilators,Mechanical, Evidence-Based Nursing, Systematic Review