ISSN 2097-6046（网络）
ISSN 2096-7446（印刷）
CN 10-1655/R
主管：中国科学技术协会
主办：中华护理学会
中华急危重症护理杂志

中华急危重症护理杂志 ›› 2026, Vol. 7 ›› Issue (6): 740-747.doi: 10.3761/j.issn.2096-7446.2026.06.018

• 证据综合研究 • 上一篇    下一篇

脓毒症患者机械通气管理的最佳证据总结

蔡莎莎1(), 帅琴燕1, 何杨梦圆1, 张美1, 项新月2, 张明月3, 黄丽华4,*()   

  1. 1 浙江大学医学院附属第一医院综合监护室 杭州市 310003
    2 浙江大学医学院附属第一医院呼吸内科 杭州市 310003
    3 浙江大学医学院附属第一医院心脏大血管外科 杭州市 310003
    4 浙江大学医学院附属第一医院护理部 杭州市 310003
  • 收稿日期:2025-08-26 出版日期:2026-06-10 发布日期:2026-06-02
  • 通讯作者: 黄丽华 E-mail:577527420@qq.com;lihuahuang818@zju.edu.cn
  • 作者简介:蔡莎莎：女，硕士，护师，E-mail：577527420@qq.com
    第一联系人：

    蔡莎莎、何杨梦圆、张美、张明月：文献检索与筛选、质量评价、证据提取、论文撰写；帅琴燕：证据校审；项新月：论文修改；黄丽华：方法学指导、研究指导

Evidence summary for the management of mechanical ventilation in patients with sepsis

CAI Shasha1(), SHUAI Qinyan1, HE Yangmengyuan1, ZHANG Mei1, XIANG Xinyue2, ZHANG Mingyue3, HUANG Lihua4,*()   

  1. 1 Department of General Intensive Care Unit， the First Affiliated Hospital，Zhejiang University School of Medicine， Hangzhou 310003， China
    2 Department of Respiratory and Critical Care Medicine， the First Affiliated Hospital，Zhejiang University School of Medicine， Hangzhou， 310003， China
    3 Department of Cardiac and Great Vessel Surgery， the First Affiliated Hospital，Zhejiang University School of Medicine， Hangzhou 310003， China
    4 Department of Nursing， the First Affiliated Hospital，Zhejiang University School of Medicine， Hangzhou 310003， China
  • Received:2025-08-26 Online:2026-06-10 Published:2026-06-02
  • Contact: HUANG Lihua E-mail:577527420@qq.com;lihuahuang818@zju.edu.cn

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摘要：

目的 检索和评价脓毒症患者机械通气管理的相关文献，对其进行总结，为临床护理工作提供循证依据。方法 根据“6S”证据资源金字塔模型，检索计算机决策系统、指南网站、专业协会网站、循证数据库、原始研究数据库中有关脓毒症患者机械通气管理的相关文献，检索时限从建库至2025年8月3日。3名研究者对纳入文献进行筛选和评价，提取相关证据。 结果 纳入14篇文献，其中指南6篇、临床决策2篇、专家共识5篇、系统评价1篇，分别从开启时机、监测评估、氧合目标、机械通气策略、注意事项5个方面形成32条最佳证据。 结论 该研究总结了脓毒症患者机械通气护理管理过程的最佳证据，为医护人员制订规范有效的护理措施、保障脓毒症患者早期恢复提供循证依据。

关键词: 脓毒症, 机械通气, 护理管理, 循证护理学, 证据总结

Abstract:

Objective To retrieve and evaluate literature on the management of mechanical ventilation in patients with sepsis，summarize the findings，and provide an evidence-based basis for clinical nursing practice. Methods Based on the 6S evidence resource pyramid model，relevant literature on the management of mechanical ventilation in patients with sepsis was searched from computerized decision-making systems，guideline websites，professional society websites，evidence-based databases，and original research databases，with the search period ranging from the inception of the database to August 3，2025. Three Researchers screened and evaluated the included literature to extract relevant evidence. Results 14 articles were included，comprising 6 guidelines，2 clinical decisions，5 expert consensuses，and a systematic review. Thirty-two best practice recommendations were synthesized across five aspects：timing of initiation，monitoring and assessment，oxygenation goals，ventilation strategies，and precautions，respectively. Conclusion This study provides a summary of the best evidence for the nursing management of mechanical ventilation in patients with sepsis. It offers an evidence-based foundation for healthcare professionals to develop standardized and effective nursing interventions and facilitate the early recovery of patients with sepsis.

Key words: Sepsis, Mechanical Ventilation, Nursing Management, Evidence-Based Nursing, Evidence Su-mmary