eISSN 2097-6046
ISSN 2096-7446
CN 10-1655/R
Responsible Institution：China Association for Science and Technology
Sponsor：Chinese Nursing Association
中华急危重症护理杂志

Chinese Journal of Emergency and Critical Care Nursing >

2025 , Vol. 6 >Issue 7: 872 - 878

DOI: https://doi.org/10.3761/j.issn.2096-7446.2025.07.019

Evidence Synthesis Research

Summary of the best evidence for skin care in adults with Stevens-Johnson syndrome and toxic epidermal necrolysis

  • ZHANG Yumei ,
  • WANG Hanmin ,
  • GUO Shuping ,
  • LANG Xiaoqing ,
  • WANG Lijuan ,
  • LI Li
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Received date: 2024-10-22

  Online published: 2025-07-04

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Abstract

Objective To conduct a comprehensive search for evidence relating to skin care for adults with Stevens-Johnson syndrome and toxic epidermal necrolysis and summarize the best evidence. Methods Systematic search of domestic and international databases，guideline websites，and websites of dermatology-related societies was conducted for clinical decisions，guidelines，evidence summaries，expert consensus，systematic reviews，and original research on skin care for adults with Stevens-Johnson syndrome and toxic epidermal necrolysis. The search timeframe was from January 2014 to September 2024. Quality assessment of the literature and extraction of information was performed independently by 4 investigators. Results A total of 12 papers were included，including one clinical decision，five guidelines，two systematic reviews，three expert consensuses，and one original study. Thirty-nine pieces of evidence encompassing five topics were summarized，including formation of multidisciplinary teams，assessment and monitoring，skin barrier care，mucosal system care，health education and follow-up. Conclusion This study summarizes the best evidence for skin care in adults with Stevens-Johnson syndrome and toxic epidermal necrolysis，can provide an evidence-based basis for clinical implementation of skin care.

Key words： Stevens-Johnson Syndrome; Toxic Epidermal Necrolysis; Skin Care; Evidence Summary; Evidence-Based Nursing

Cite this article

ZHANG Yumei , WANG Hanmin , GUO Shuping , LANG Xiaoqing , WANG Lijuan , LI Li . Summary of the best evidence for skin care in adults with Stevens-Johnson syndrome and toxic epidermal necrolysis[J]. Chinese Journal of Emergency and Critical Care Nursing, 2025 , 6(7) : 872 -878 . DOI: 10.3761/j.issn.2096-7446.2025.07.019

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