eISSN 2097-6046
ISSN 2096-7446
CN 10-1655/R
Responsible Institution：China Association for Science and Technology
Sponsor：Chinese Nursing Association
中华急危重症护理杂志

Chinese Journal of Emergency and Critical Care Nursing >

2026 , Vol. 7 >Issue 1: 61 - 69

DOI: https://doi.org/10.3761/j.issn.2096-7446.2026.01.009

Special Planning——Critical Pediatric Care

Best evidence summary for family participatory non-pharmacological management of procedural pain in NICU neonates

  • FENG Lu ,
  • LI Yan ,
  • JING Jie ,
  • NIE Xinyue ,
  • HU Huan ,
  • TANG Binzhi
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  • 1. Department of Pediatric Surgery， Sichuan Provincial People’s Hospital，University of Electronic Science and Technology of China， Chengdu 610072， China
    2. Department of Nephrology， Sichuan Provincial People’s Hospital，University of Electronic Science and Technology of China， Chengdu 610072， China
    3. Department of Nursing， Sichuan Provincial People’s Hospital，University of Electronic Science and Technology of China， Chengdu 610072， China
    4. Department of Emergency Intensive Care Unit， Sichuan Provincial People’s Hospital，University of Electronic Science and Technology of China， Chengdu 610072， China
    5. Department of Pediatrics， Sichuan Provincial People’s Hospital，University of Electronic Science and Technology of China， Chengdu 610072， China

Received date: 2025-01-20

  Online published: 2026-01-06

Supported by

2024 Sichuan Medical Association Medical Research Project(S2024013)

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Abstract

Objective To summarize the evidence for family participatory non-pharmacological management of procedural pain in NICU neonates，and to provide a basis for clinical practice. Methods Domestic and foreign databases and relevant websites were systematically searched for the literature on family participatory non-pharmacological management of procedural pain in NICU neonates. The retrieval time limit was from the establishment of the database until March 2024，and the evidence was extracted and summarized after a quality assessment of the literature. Results A total of 26 pieces of literature were included，including two clinical decisions，six guidelines，an expert consensus，eight evidence summaries，and nine system reviews. 41 pieces of evidence were summarized in eight areas，including institutional norms，environmental facilities，multidisciplinary team，training and education，communication and support，pain assessment，non-pharmacological interventions，and effectiveness evaluation. Conclusion The best evidence summarized in this study can provide evidence-based basis for clinical healthcare professionals to target the application of evidence.

Key words： Intensive Care Units; Neonatal; Procedural Pain; Family Involvement; Non-Pharmacological Management; Evidence-Based Nursing

Cite this article

FENG Lu , LI Yan , JING Jie , NIE Xinyue , HU Huan , TANG Binzhi . Best evidence summary for family participatory non-pharmacological management of procedural pain in NICU neonates[J]. Chinese Journal of Emergency and Critical Care Nursing, 2026 , 7(1) : 61 -69 . DOI: 10.3761/j.issn.2096-7446.2026.01.009

References

[1] 吴玉洁, 吴利平, 冷虹瑶, 等. 儿童操作性疼痛常见非药物疗法的最佳证据总结[J]. 护理研究, 2021, 35(5):782-788.
  Wu YJ, Wu LP, Leng HY, et al. Best evidence summary for non-pharmaceutical therapy of procedural pain in children[J]. Chin Nurs Res, 2021, 35(5):782-788.
[2] Bueno M, Rao M, Aujla P, et al. A scoping review of the epidemiology and treatment of painful procedures in hospitalized neonates:what has changed in the past three decades?[J]. Eur J Pain, 2024, 28(9):1468-1485.
[3] McPherson C, Miller SP, El-Dib M, et al. The influence of pain,agitation,and their management on the immature brain[J]. Pediatr Res, 2020, 88(2):168-175.
[4] Eissler AB, Zwakhalen S, Stoffel L, et al. Systematic review of the effectiveness of involving parents during painful interventions for their preterm infants[J]. J Obstet Gynecol Neonatal Nurs, 2022, 51(1):6-15.
[5] van der Vaart M, Hauck AGV, Mansfield R, et al. Parental experience of neonatal pain research while participating in the Parental touch trial(Petal)[J]. Pain, 2024, 165(8):1727-1734.
[6] 胡雁, 郝玉芳. 循证护理学[M]. 2版. 北京: 人民卫生出版社, 2018.
  Hu Y, Hao YF. Evidence-based nursing[M]. 2nd ed. Beijing: People’s Medical Publishing House, 2018.
[7] Alper BS, Brian Haynes R. EBHC pyramid 5.0 for accessing preappraised evidence and guidance[J]. Evid Based Med, 2016, 21(4):123-125.
[8] Foster MJ, Shurtz S. Making the critical appraisal for summaries of evidence(CASE) for evidence-based medicine(EBM):critical appraisal of summaries of evidence[J]. J Med Libr Assoc, 2013, 101(3):192-198.
[9] Shea BJ, Reeves BC, Wells G, et al. AMSTAR 2:a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions,or both[J]. BMJ, 2017,358:j4008.
[10] Roué JM. Assessment of pain in neonates[EB/OL]. (2024-03-16)[2024-12-10]. https://www.uptodate.cn/contents/zh-Hans/assessment-of-pain-in-neonates?search=Assessment%20of%20pain%20in%20neonates&source=search_result&selectedTitle=1%7E150&usage_type=default&display_rank=1.
[11] Roué JM. Management and prevention of pain in neonates[EB/OL].(2024-03-16)[2024-12-10]. https://www.uptodate.cn/con-tents/zh-Hans/management-and-prevention-of-pain-in-neonates?se-arch=%E6%96%B0%E7%94%9F%E5%84%BF%E7%96%BC%E7%97%9B&source=search_result&selectedTitle=1%7E15&usa-ge_type=default&display_rank=1.
[12] 沈巧, 郑显兰, 史源, 等. 中国新生儿疼痛管理循证指南(2023年)[J]. 中国当代儿科杂志, 2023, 25(2):109-127.
  Shen Q, Zheng XL, Shi Y, et al. Evidence-based guideline for neonatal pain management in China(2023)[J]. Chin J Contemp Pediatr, 2023, 25(2):109-127.
[13] Davidson JE, Aslakson RA, Long AC, et al. Guidelines for fa-mily-centered care in the neonatal,pediatric,and adult ICU[J]. Crit Care Med, 2017, 45(1):103-128.
[14] Lago P, Garetti E, Bellieni CV, et al. Systematic review of nonpharmacological analgesic interventions for common needle-related procedure in newborn infants and development of evidence-based clinical guidelines[J]. Acta Paediatr, 2017, 106(6):864-870.
[15] AAP COMMITTEE ON FETUS AND NEWBORN and SECTION ON ANESTHESIOLOGY AND PAIN MEDICINE. Prevention and management of procedural pain in the neonate:an update[J]. Pediatrics, 2016, 137(2):e20154271.
[16] 中国医师协会新生儿科医师分会循证专业委员会. 早产儿和低出生体重儿袋鼠式护理临床实践指南(2022)[J]. 中国循证医学杂志, 2023, 23(3):249-264.
  Evidence-Based Medicine Group, Neonatologist Society,Chinese Medical Doctor Association. Clinical practice guidelines for kangaroo mother care in preterm and low birth weight infants(2022)[J]. Chin J Evid Based Med, 2023, 23(3):249-264.
[17] 中华医学会儿科学分会新生儿学组, 中国医药教育协会新生儿专业委员会, 黑明燕, 等. 新生儿重症监护病房家庭参与式照护实践指南[J]. 中华儿科杂志, 2023, 61(4):292-300.
  The Group of Neonatology,Society of Pediatrics Chinese Medical Association; Neonatal Professional Committee Chinese Association of Medical Education; Hei MY, et al. Guidelines for family integrated care in neonatal intensive care unit[J]. Chin J Pediatr, 2023, 61(4):292-300.
[18] 程锐, 杨洋, 史源, 等. 新生儿疼痛评估与镇痛管理专家共识(2020版)[J]. 中国当代儿科杂志, 2020, 22(9):923-930.
  Cheng R, Yang Y, Shi Y, et al. Expert consensus on neonatal pain assessment and analgesia management(2020 edition)[J]. Chin J Contemp Pediatr, 2020, 22(9):923-930.
[19] Johal J. Procedural pain(newborns): assessment[EB/OL]. (2022-11-25)[2024-08-29]. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI117520.
[20] Whitehorn A, Porritt K. Procedural pain(newborns): breastfeeding[EB/OL]. (2023-07-24)[2024-08-29]. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI1263.
[21] Johal J. Procedural pain(newborns): facilitated tucking[EB/OL]. (2022-11-25)[2024-08-29]. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI117522.
[22] Johal J. Procedural pain(newborns): non-nutritive sucking[EB/OL]. (2021-08-06)[2024-08-29]. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI112321.
[23] Whitehorn A, Porritt K. Procedural pain(newborns): skin-to-skin[EB/OL]. (2022-04-26)[2024-08-29]. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=jbi&NEWS=N&AN=JBI24683.
[24] 王瑞娜, 赖晓帆, 刘秋利, 等. 预防新生儿足底采血疼痛的最佳证据总结[J]. 护理学报, 2019, 26(11):45-48.
  Wang RN, Lai XF, Liu QL, et al. Best evidence summary for pain relief of capillary blood sampling[J]. J Nurs China, 2019, 26(11):45-48.
[25] 路简羽, 岳洁雅, 袁艳丽, 等. 早产儿袋鼠式护理方法的最佳证据总结[J]. 中华现代护理杂志, 2019, 25(22):2778-2782.
  Lu JY, Yue JY, Yuan YL, et al. Summary of best evidence on kangaroo mother care for premature infants[J]. Chin J Mod Nurs, 2019, 25(22):2778-2782.
[26] Johnston C, Campbell-Yeo M, Disher T, et al. Skin-to-skin care for procedural pain in neonates[J]. Cochrane Database Syst Rev, 2017, 2(2):CD008435.
[27] Shah PS, Torgalkar R, Shah VS. Breastfeeding or breast milk for procedural pain in neonates[J]. Cochrane Database Syst Rev, 2023, 8(8):CD004950.
[28] Pirlotte S, Beeckman K, Ooms I, et al. Non-pharmacological interventions for the prevention of pain during endotracheal suctioning in ventilated neonates[J]. Cochrane Database Syst Rev, 2024, 1(1):CD013353.
[29] Wade CA, Frazer JS, Qian E, et al. Development of locally relevant clinical guidelines for procedure-related neonatal analgesic practice in Kenya:a systematic review and meta-analysis[J]. Lancet Child Adolesc Health, 2020, 4(10):750-760.
[30] Weng YW, Zhang J, Chen ZF. Effect of non-pharmacological interventions on pain in preterm infants in the neonatal intensive care unit:a network meta-analysis of randomized controlled trials[J]. BMC Pediatr, 2024, 24(1):9.
[31] Ting B, Tsai CL, Hsu WT, et al. Music intervention for pain control in the pediatric population:a systematic review and meta-analysis[J]. J Clin Med, 2022, 11(4):991.
[32] Francisco ASPG, Montemezzo D, Ribeiro SNDS, et al. Positioning effects for procedural pain relief in NICU:systematic review[J]. Pain Manag Nurs, 2021, 22(2):121-132.
[33] De Clifford-Faugere G, Lavallée A, Khadra C, et al. Systematic review and meta-analysis of olfactive stimulation interventions to manage procedural pain in preterm and full-term neonates[J]. Int J Nurs Stud, 2020, 110:103697.
[34] Neshat H, Hassankhani H, Negarandeh R, et al. Care providers’ experiences regarding barriers to maternal participation in neonatal pain management[J]. Nurs Crit Care, 2023, 28(2):245-252.
[35] Balice-Bourgois C, Zumstein-Shaha M, Simonetti GD, et al. Interprofessional collaboration and involvement of parents in the management of painful procedures in newborns[J]. Front Pediatr, 2020, 8:394.
[36] 周菁鑫, 严洁, 俞群. 父母参与新生儿疼痛管理的研究进展[J]. 中国护理管理, 2019, 19(1):151-155.
  Zhou JX, Yan J, Yu Q. Research progress on involvement of parents in neonatal pain management[J]. Chin Nurs Manag, 2019, 19(1):151-155.
[37] 谭彦娟, 杨斯钰, 陈羽双, 等. 家庭参与式护理在缓解NICU早产儿操作性疼痛中的应用[J]. 中国护理管理, 2020, 20(7):1103-1107.
  Tan YJ, Yang SY, Chen YS, et al. The implementation of family integrated-care for procedural pain among premature infants in the Neonatal Intensive Care Unit[J]. Chin Nurs Manag, 2020, 20(7):1103-1107.
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