Objective To formulate a follow-up checklist for postoperative patients of pancreatic cancer undergoing radical resection combined with intestinal autotransplantation，and provide a scientific tool to support the follow-up work，timely identify and solve problems encountered by patients after discharge，and ensure the long-term efficacy. Methods The first draft of the follow-up checklist was constructed through literature review，and the final draft of the follow-up checklist was formed by conducting 2 rounds of correspondence with 14 experts using the Delphi method in September 2024，screening experts’ opinions and revising and improving the checklist. The convenience sampling method was adopted to select 14 postoperative patients of pancreatic cancer with radical resection combined with intestinal autotransplantation from a tertiary class A hospital in Zhejiang Province in November 2024 as the research subjects. The nurses conducted telephone follow-up to the patients with the postoperative follow-up list and evaluated the follow-up list. Results The effective response rates of 2 rounds of expert consultations were 93.33% and 100%，the authoritative coefficients were 0.939 and 0.947，the variation coefficients of each item ranged from 0 to 0.167 and from 0 to 0.141，and the Kendall harmony coefficient was 0.137 and 0.140（P<0.05）. The final follow-up checklist included 3 primary indicators，12 secondary indicators and 27 tertiary indicators. Both nurses and patients believed that the follow-up checklist was comprehensive with strong professional and clinical practicability. Conclusion The follow-up checklist is reasonable in structure，comprehensive in content，specialized and practical，which can provide a scientific and standardized tool to support post-discharge follow-up of pancreatic cancer patients undergoing radical resection combined with intestinal autotransplantation.