eISSN 2097-6046
ISSN 2096-7446
CN 10-1655/R
Responsible Institution：China Association for Science and Technology
Sponsor：Chinese Nursing Association
中华急危重症护理杂志

Chinese Journal of Emergency and Critical Care Nursing >

2025 , Vol. 6 >Issue 11: 1292 - 1296

DOI: https://doi.org/10.3761/j.issn.2096-7446.2025.11.002

Research Paper

The effect of high-flow nasal cannula on thirst sensation and degree of mouth dryness after extubation in mechanically ventilated patients

  • TANG Qi ,
  • YANG Baoyi ,
  • WANG Rong
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  • Department of Critical Care Medicine，Taihe Hospital，Shiyan，Hubei University of Medicine，Shiyan，442000，China

Received date: 2025-01-13

  Online published: 2025-11-04

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Abstract

Objective To compare and analyze the effects of high-flow nasal cannula（HFNC） and conventional oxygen therapy（COT） on thirst and dry mouth after extubation in mechanically ventilated patients. Methods A prospective cohort study was applied. Conveniently selected 226 patients who underwent mechanical ventilation and were hospitalized in the ICU of a tertiary Grade A hospital in Shiyan City from May 2022 to April 2024 as the study subjects. According to the oxygen therapy plan after extubation，patients were divided into HFNC group and COT group. Propensity Score Matching（PSM） was applied to balance the general information of two groups of patients. The degree of thirst and dry mouth after extubation were compared and analyzed between two groups. Results After PSM，multiple indicators were matched and balanced in both HFNC and COT groups，with improved comparability（P>0.05）. 4 and 24 hours after extubation，the degree of thirst in the HFNC group was significantly reduced compared to the COT group（P<0.05）. However，there was no significant difference in the degree of dry mouth between the two groups. There was no correlation between thirst sensation and oral dryness after extubation among HFNC and COT patients（P>0.05）. Conclusion Compared with COT，HFNC therapy can reduce the intensity of thirst in mechanical ventilation patients within 24 hours after extubation，but has no significant effect on the degree of dry mouth in patients.

Key words： High Flow Nasal Cannula; Extubation; Thirst; Dry Mouth; Nursing Care

Cite this article

TANG Qi , YANG Baoyi , WANG Rong . The effect of high-flow nasal cannula on thirst sensation and degree of mouth dryness after extubation in mechanically ventilated patients[J]. Chinese Journal of Emergency and Critical Care Nursing, 2025 , 6(11) : 1292 -1296 . DOI: 10.3761/j.issn.2096-7446.2025.11.002

References

[1] Gunnels MS, Reisdorf EM, Mandrekar J, et al. Assessing discomfort in American adult intensive care patients[J]. Am J Crit Care, 2024, 33(2):126-132.
[2] Flim M, Hofhuis J, Spronk P, et al. Measuring thirst distress of patients in the intensive care unit[J]. Nurs Crit Care, 2022, 27(4):576-582.
[3] Negro A, Villa G, Greco M, et al. Thirst in patients admitted to intensive care units:an observational study[J]. Ir J Med Sci, 2022, 191(5):2283-2289.
[4] 苏英, 刘清. 气管插管机械通气患者拔管后获得性吞咽功能障碍危险因素分析[J]. 护士进修杂志, 2022, 37(3):276-279.
  Su Y, Liu Q. Risk factors of acquired post-extubation dysphagia in patients with endotracheal intubation and mechanical ventilation[J]. J Nurses Train, 2022, 37(3):276-279.
[5] Zheng XZ, Wang R, Giri M, et al. Efficacy of preventive use of oxygen therapy after planned extubation in high-risk patients with extubation failure:a network meta-analysis of randomized controlled trials[J]. Front Med(Lausanne), 2022,13:9:1026234.
[6] 孙振球, 徐勇勇. 医学统计学[M]. 4版. 北京: 人民卫生出版社,2014:573.
  Sun ZQ, Xu YY. Medical statistics[M]. 4th ed. Beijing: People's Medical Publishing House,2014:573.
[7] 张玉梅, 宋鲁平. 康复评定常用量表[M]. 北京: 科学技术文献出版社,2018:466.
  Zhang YM, Song LP. Common scale for rehabilitation assess-ment[M]. Beijing: Scientific and Technical Documents Publishing House,2018:466.
[8] 陈健, 卢咏梅, 吴风玲, 等. 乌梅喷雾剂缓解胃肠道术后口干症的实验及临床应用研究[J]. 护理研究, 2011, 25(27):2475-2476.
  Chen J, Lu YM, Wu FL, et al. Study on experiments and clinical application of dark plum aerosol to relieve xerostomia of postoperative patients after accepting gastrointestinal tract operation[J]. Chin Nurs Res, 2011, 25(27):2475-2476.
[9] Plotnikow GA, Villalba D, Gogniat E, et al. Performance of different active humidification systems in high-flow oxygen therapy[J]. Respir Care, 2020, 65(9):1250-1257.
[10] Hsu LM, Yang JT, Wen XY, et al. Human thirst behavior requires transformation of sensory inputs by intrinsic brain networks[J]. BMC Biol, 2022, 20(1):255.
[11] 杨帆. 急性缺氧大鼠水代谢紊乱的机制研究[D]. 重庆: 第三军医大学, 2017.
  Yang F. Study on the mechanism of water metabolism disorder in rats with acute hypoxia[D]. Chongqing: Third Military Medical University, 2017.
[12] Chen XQ, Tan CP, Jiang HJ. High-flow nasal cannula oxygen therapy is superior to conventional oxygen therapy in intensive care unit patients after extubation[J]. Am J Transl Res, 2023, 15(2):1239-1246.
[13] Shen YM, Xu Y, Xu FL, et al. Effect of high-flow nasal cannula oxygen therapy on hypoxemia in patients after esophagectomy[J]. Can Respir J, 2025,2025:4691604.
[14] Lewis SR, Baker PE, Parker R, et al. High-flow nasal cannulae for respiratory support in adult intensive care patients[J]. Cochrane Database Syst Rev, 2021, 3(3):CD010172.
[15] Zhao P, Luo YS, Xiang LJ, et al. Dynamic change and risk factors of intense thirst in patients admitted to neuro-intensive care unit:an observational study[J]. Nurs Crit Care, 2024.
[16] Doi S, Nakanishi N, Kawahara Y, et al. Impact of oral care on thirst perception and dry mouth assessments in intensive care patients:an observational study[J]. Intensive Crit Care Nurs, 2021,66:103073.
[17] Chen YQ, Wang CL, Chiu AH, et al. Chewing gum may alleviate degree of thirst in patients on hemodialysis[J]. Medicina, 2024, 60(1):2.
[18] 罗倩, 李静, 杨明静, 等. 不同给水方式对机械通气病人口渴和并发症发生率的影响[J]. 护理研究, 2023, 37(17):3049-3055.
  Luo Q, Li J, Yang MJ, et al. Effects of different water supply methods on thirst and complications occurrence in mechanically ventilated patients[J]. Chin Nurs Res, 2023, 37(17):3049-3055.
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