Abstract: Objective To identify the risk factors of intra-abdominal hypertension among adult ICU patients by meta-analysis. Methods We searched databases including CNKI,Wanfang Data,VIP,CBM,Cochrane Library,PubMed,Web of Science and Embase from inception to December 2022,to collect studies on risk factors for intra-abdominal hypertension of adult ICU patients. 2 reviewers independently screened literature according to the inclusion and exclusion criteria,extracted data,and assessed the quality of included studies. Meta-analysis was conducted by RevMan 5.4. Results A total of 17 pieces of the literature involving 3 250 adult ICU patients were included. The statistically risk factors were BMI（MD=3.09）,24 h fluid input（MD=0.98）,mechanical ventilation（OR=3.40）,PaO₂/FiO₂（MD=-17.18）,APACHEⅡ Score（MD=4.04）,sepsis（OR=2.42）,intestinal obstruction（OR=11.67）,abdominal surgery（OR=2.10）. Conclusion Higher BMI,larger 24 h fluid input,higher APACHEⅡ Score,lower PaO₂/FiO₂,mechanical ventilation,sepsis,intestinal obstruction and abdominal surgery were independent predictors for intra-abdominal hypertension in adult ICU patients. Medical staff should dynamically assess the intra-abdominal pressure and take targeted and individualized interventions to prevent the occurrence of intra-abdominal hypertension.

Key words: Intensive Care Units, Intra-abdominal Hypertension, Risk Factors, Meta-Analysis, Evidence-Based Nursing