In order to fight against the  sudden outbreak  of  COVID-19,  the  nursing department of  our hospitalquickly established and operated a nursing management organizational structure,  prepared various units for the di-agnosis and treatment of patients with  COVID19,conducted effective human resource deployment and  comprehen-sive staff training,  implement comprehensive and seamless measures,  and controled key procedures accurately and scientifically to ensure timely treatment of patients and prevent the spread of the virus in the hospital. This article summarized the practical experience of nursing management in epidemic  prevention and  control to provides reference for the response to the similar public health emergencies in the future.