Abstract: To summarize the nursing experience of a child with Prader-Willi syndrome complicated with pulmonary infection and secondary septic shock. In view of the rapid progress of septic shock in children,difficulty to effectively remove respiratory secretions,complicated medication,and being prone to complications,nursing points included：the application of specific indicators to effectively identify the signs of shock and close cooperation for rescue between doctors and nurses; bronchoalveolar lavage combined with lung ultrasound to guide chest physical therapy to remove secretions and promote lung recruitment; accurate medication,close monitoring of drug efficacy and side effects; prevention of pressure injury and acute kidney injury. After 30 days of careful treatment and care,the child was discharged in stable condition and recovered well during outpatient follow-up.

Key words: Prader-Willi Syndrome, Sepsis, Shock,Septic, Emergency Nursing