Abstract:

Objective To investigate the effect of peripheral perfusion index combined with sequential organ failure score in predicting acute skin failure in ICU patients. Methods A total of 217 patients admitted to the ICU of a grade-Ⅲ Class A general hospital in Shandong Province from March 2023 to September 2023 were selected by convenience sampling method as the study objects. According to whether they had acute skin failure，they were divided into skin failure group（n=50） and non-skin failure group（n=167）.By comparing the data of the two groups，the area under receiver operating characteristic（ROC） curve was used to analyze the predictive value of peripheral perfusion index combined with sequential organ failure score in acute skin failure. Results Pearson correlation analysis showed that there was a significant negative correlation between peripheral perfusion index and sequential organ failure score（r=-0.589，P<0.05）. The area under ROC curve of peripheral perfusion index combined with sequential organ failure score was 0.948，sensitivity was 0.898，and specificity was 0.905. The Jorden index was 0.803. Conclusion The combination of peripheral perfusion index and sequential organ failure score can effectively predict the occurrence of acute skin failure in ICU patients，which can provide reference for clinical staff to monitor and intervene early in ICU patients with skin failure.

Key words: ICU, Peripheral Perfusion Index, Sequential Organ Failure Assessment, Acute Skin Failure, Prediction Model, Risk Factor