预防性接触隔离集束化措施对ICU多重耐药菌感染防控效果的研究

doi:10.3761/j.issn.2096-7446.2025.09.015

Abstract

Abstract:

Objective To explore the effect of preventive contact isolation cluster measures on the prevention of multidrug-resistant organisms in ICU patients，based on the propensity score matching method（PSM）. Methods 660 adult patients were collected. According to the implementation of preventive contact isolation cluster measures，they were divided into implementation group and non-implementation group. 177 cases were in the implementation group and 483 cases were in the non-implementation group. The patients in the two groups were matched 1 ∶ 1 by the propensity score matching method. Matching variables were those that showed statistical differences in univariate analysis and common influencing factors between the two groups，including admission route，history of surgery，APACHE Ⅱ score，septic shock，use of hormones or immunosuppressants，C-reactive protein and the length of stay in ICU. After final matching，107 patients were included in each group，and the occurrence of nosocomial infection and multidrug-resistant organisms infection between the two groups were compared. Results There were no significant differences in baseline data，APACHE Ⅱ score and other risk factors between the two groups after PSM （P>0.05）. The incidence of nosocomial infection in the implementation group was slightly lower than that in the non-implementation group，and the difference was statistically significant（P<0.05），but there was no statistically significant difference in the incidence of multidrug-resistant organisms between the two groups（P>0.05）. Conclusion The implementation of preventive contact isolation cluster measures for high-risk patients has a certain effect on reducing the nosocomial infection rate in ICU，but the incidence of multidrug-resistant organisms has not been significantly reduced. In the future，it is hoped that empirical isolation will be transformed into the scientific and accurate screening of risk patients，and standardized intervention programs will be formulated and implemented.

Key words: ICU, Nursing Care, Infection Control, Multidrug-Resistant Organisms, Contact Isolation, Propensity Score Matching

YUAN Cui, XIAO Yanyan, CHEN Kaisheng, WANG Fang, WANG Yi, HU Meihua, YAO Xi, WANG Dongxin, LI Shuangling. The effect of preventive contact isolation cluster measures on the prevention of multidrug-resistant organisms in ICU patients[J]. Chinese Journal of Emergency and Critical Care Nursing, 2025, 6(9): 1106-1111.

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The effect of preventive contact isolation cluster measures on the prevention of multidrug-resistant organisms in ICU patients

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