Abstract: Objective A simple and practical rehabilitation system for patients in ICU was developed based on virtual reality（VR）technology to improve patients' rehabilitation compliance and safety. Methods By employing interdisciplinary and literary research methodologies,we employed 3DMax and Maya modeling software,and utilized the Unity 3D game engine for interactive purposes,a VR rehabilitation training system was developed for ICU patients. The convenience sampling method was employed to select 3 conscious patients who were admitted to the ICU of a Grade 3A Hospital in Shandong Province between April and June 2023. These patients were subjected to intervention using the VR rehabilitation system,and the applicability evaluation of VR rehabilitation system was evaluated from the aspects of adverse events,system availability and subjects' application feelings. Results The rehabilitation system designed in this study included upper limbs,lower limbs,cognitive function and strength training. The system was easy to operate,easy to understand and interesting,and no adverse events occurred during the intervention period. Conclusion The study has developed a VR-based rehabilitation training system,which demonstrates a certain degree of efficacy in promoting the rehabilitation of patients in ICU. Moreover,the system exhibits a low cost and a relatively safe implementation process. However,it is imperative to conduct future investigations involving a large sample size and multiple centers to validate its clinical effectiveness.

Key words: Virtual Reality, Critical Illness, Intensive Care Units, Rehabilitation Nursing