Abstract: Objective To investigate the variability of blood pressure in hospitalized patients with aortic dissection and explore its influencing factors. Methods We collected the data of 346 patients with aortic dissection admitted to a tertiary first-class hospital in Wuhan city from January 2019 to June 2020. The related factors that may affect the variability of blood pressure were analyzed by multiple linear regression. Results The variability of systolic blood pressure in inpatients with aortic dissection was （11.65± 3.60） mmHg（1 mmHg=0.133 kPa）,the varia-bility of diastolic blood pressure was （8.03± 1.98） mmHg. Gender,age,history of hypertension,smoking his-tory,alcohol drinking history,first admission blood pressure and types of antihypertensive drugs were the main influencing factors of blood pressure variability（P< 0.05）. Conclusion Blood pressure in patients with aortic dissec-tion fluctuated to a certain extent during hospitalization. It is suggested that medical staff should reduce the fluctuation of blood pressure while controlling the blood pressure of patients,so as to reduce the risk of deterioration and death,and improve the prognosis of patients.

Key words: Dissection of Aorta, Blood Pressure Variability, Inpatients, Factor Analysis, Statistical, Critical Care Nursing