Abstract:

Objective To comprehensively search，evaluate and summarize the best evidence of blood pressure management in the acute phase of ischemic stroke，to provide reference for blood pressure management and monitoring. Methods Based on the 5S model of the evidence hierarchy，a systematic search was conducted across major domestic and international databases，relevant evidence-based resources，and professional association websites to retrieve all pertinent evidence，including clinical decision-making，best practices，evidence summaries，clinical guidelines，and systematic reviews. The search time limit was from the establishment of databases to December 10，2024. Two researchers independently evaluated the quality of the literature，extracted and summarized the evidence. Results A total of 22 studies were included，including 2 clinical decision-making resources，4 guidelines，and 16 systematic reviews. The best evidence included 20 recommendations in 5 aspects，including blood pressure management principles and objectives，blood pressure management during intravenous thrombolysis，mechanical thrombectomy，non-reperfusion treatment，and recovery phase management. Conclusion This study summarized the beat evidence of blood pressure management in the acute-phase of ischemic stroke. The overall level of the quality and level of the evidence is high，which has guiding significance for clinical medical staff to carry out scientific and effective blood pressure management. It can formulate targeted blood pressure management plans according to the actual situation of clinical work，and improve the blood pressure of patients.

Key words: Ischemic Stroke, Acute, Blood Pressure, Evidence Summary, Evidence-Based Nursing