Abstract:

Objective To investigate the effects of the goal-oriented mobilization based on the Johns Hopkins Highest Level of Mobility in ICU patients with difficult weaning from mechanical ventilation. Methods Patients with weaning difficulties from ICU of a tertiary class A hospital in Guangzhou City from July 2023 to December 2024 were selected as the experimental group，and early mobilization based on the Johns Hopkins Highest Level of Mobility was implemented. Patients with weaning difficulties admitted from January 2022 to June 2023 were selected as control group，and routine rehabilitation training was carried out. The incidence of ICU acquired weakness，length of stay in ICU，duration of mechanical ventilation and success rate of weaning were compared between the two groups. Results 96 patients completed the study，including 48 in the control group and 48 in the experimental group. The incidence rate of ICU acquired weakness and weaning success rate of the experimental group were higher than those in the control group，and the differences were statistically significant（P<0.05）. The length of stay in ICU and mechanical ventilation time of the experimental group were lower and the differences were statistically significant（P<0.05）. Conclusion Goal-oriented early mobilization based on the Johns Hopkins Highest Level of Mobility can effectively reduce the incidence of ICU acquired weakness，shorten ICU stay and mechanical ventilation duration，improve weaning success rate，and accelerate patient recovery.

Key words: Johns Hopkins Highest Level of Mobility, Mechanical Ventilation, Difficult Weaning, Rehabili-tation Nursing