Abstract: Objective To analyze and compare the difference of early intervention effect of initiating the rapid response system（RRS）between hospitalized and non-hospitalized patients. Methods The RRS events initiated in a tertiary class A hospital in Zhejiang Province from January 2016 to December 2021 were collected retrospectively. Differences of initiating time,reasons,personnel and patient outcome between hospitalized and non-hospitalized patients were analyzed. Results From 2016 to 2021,983 RRS events were initiated,including 715 inpatients（72.74%）and 268 non-hospitalized patients（27.26%）. The main initiators of RRS were nurses（94.80%）. The res-ponse time of the emergency medical team（MET）after the initiation of RRS was 3（2,4）minutes and 2（1,3）minutes for inpatients and non-hospitalized patients respectively. The visiting departments were surgery（55.81%）and cardiovascular medicine（31.34%）. The main reasons for initiating RRS were sudden loss of consciousness（69.23%）and witnessing patients falling to the ground suddenly（57.84%）. Most required on-site intervention（92.77%）after the initiation of RRS. There was no particularity in the distribution of RRS initiating time periods for inpatients,while the initiating time of RRS for non-hospitalized patients was from 08：00 to 16：00. Conclusion Under homogeneous management,both inpatients and non-hospitalized patients reached MET within 5 minutes after the initiation of RRS. Non-hospitalized patients differed from hospitalized patients in terms of time,place,reasons,and outcome. Attention needs to be paid to the initiation of RRS when the condition of non-hospitalized patients suddenly change in the hospital. It is recommended to carry out RRS-related training and simulation exercises for all personnel in the hospital.

Key words: Rapid Response Systems, Emergency Medical Services, Inpatients, Non-Hospitalized Patients, Nursing Administration Research