目的 构建ICU护士用药安全风险评价指标体系。方法 在“M-SHEL”模型理论基础上，采用文献分析法、焦点团体访谈法、德尔菲法及层次分析法，筛选风险评价指标，完成各级指标权重赋值，构建ICU护士用药安全风险评价指标体系。结果 2轮专家函询问卷回收率分别为100%和96.15%，两轮的权威系数分别为0.873和0.876，肯德尔和谐系数分别为0.159和0.226，最终构建的ICU护士用药安全风险评价指标体系包含5项一级指标（软件风险、硬件风险、环境风险、人员风险和管理风险）、11项二级指标和47项三级指标。结论 ICU护士用药安全风险评价指标体系具有较强的科学性与实用性，可为ICU护士实施护理用药安全风险评价提供客观、可量化的科学依据。

Objective To construct a risk assessment index system for medication safety in ICU nurses. Methods Based on the theory of the “M-SHEL” model，literature review，focus group interviews，Delphi method，and analytic hierarchy process were used to screen risk assessment indicators，complete the weight assignment of indicators at all levels，and construct an ICU medication safety risk assessment index system. Results The recovery rates of the two rounds of expert consultation were 100% and 96.15%，respectively. The authority coefficient of the two rounds was 0.873 and 0.876 respectively，and the Kendall harmony coefficient was 0.159 and 0.226 respectively. The final ICU medication safety risk assessment index system consists of five first level indicators（software risk，hardware risk，environment risk，liveware risk and management risk），11 second level indicators and 47 third level indicators. Conclusion The ICU medication safety risk evaluation index system has strong scientific and practicability，which can provide an objective and quantifiable scientific basis for ICU nursing staff to implement medication safety risk assessment.