目的 总结并应用儿科重症监护病房患儿外周动脉导管置入的最佳证据。方法 遵循乔安娜布里格斯研究所循证护理模式，结合渥太华模型，将前期研究中的10条危重症患儿外周动脉导管置入与管理的最佳证据转化为12条审查指标，比较基线审查期和证据应用再审查期护士执行率、首次穿刺成功率及并发症发生率。结果 证据应用再审查期，外周动脉导管置入的12条临床审查指标执行率整体呈上升趋势（48.24%与80.22%，χ²=189.379，P<0.001）；评估及置入维度执行率明显提高（P<0.001），其中外周动脉导管适应证评估、凝血功能评估、侧支循环监测、置管资质、感染预防及疼痛管理7条指标显著增高（P<0.05）。证据应用再审查期，首次穿刺成功率显著提高（58.9%与82.2%，χ²=10.899，P=0.001）；穿刺并发症发生率明显降低（22.4%与4.2%，χ²=11.208，P<0.001）。结论 将危重症患儿外周动脉导管置入的最佳证据应用于临床，可规范护士行为，提高护士循证证据执行率，预防相关并发症发生。

Objective To synthesize and apply the best evidence of peripheral arterial catheter（PAC） placement in the pediatric intensive care unit（PICU）. Methods Utilizing the Joanna Briggs Institute（JBI） evidence-based nursing framework and the Ottawa Model of Research Use，ten pieces of best evidence were discerned and converted into twelve clinical audit criteria. A comparative analysis was performed the baseline phase and the post-implementation re-audit phase to evaluate nurses’ adherence to evidence，initial success rates of PAC insertion，and the occurrence of complications. Results During the post-implementation re-audit phase，total compliance with the 12 audit criteria markedly improved（48.24% vs. 80.22%，χ²=189.379，P<0.001）. Significant enhancements were noted in both the assessment and insertion domains（P<0.001），with seven critical indicators—evaluation of indications，coagulation status assessment，collateral circulation，operator qualifications，infection prevention，and pain management—demonstrating statistically significant increases（P<0.05）. The success rate of initial attempts dramatically increased（58.9% vs. 82.2%，χ²=10.899，P=0.001），while the occurrence of insertion-related problems greatly diminished（22.4% vs. 4.2%，χ²=11.208，P<0.001）. Conclusion The best evidence application of PAC insertion into nursing practice in the PICU can standardize nurses’ behavior，improve evidence adherence of nurses，and prevent procedure-related complications in critically ill pediatric patients.