ISSN 2097-6046（网络）
ISSN 2096-7446（印刷）
CN 10-1655/R
主管：中国科学技术协会
主办：中华护理学会
中华急危重症护理杂志

中华急危重症护理杂志 >

2026 , Vol. 7 >Issue 2: 223 - 230

DOI: https://doi.org/10.3761/j.issn.2096-7446.2026.02.017

证据综合研究

血栓后综合征患者结局自我报告工具的系统评价

  • 张莉莉 ,
  • 张焱 ,
  • 王方方 ,
  • 黄丽华 ,
  • 尹慧芳
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  • 1.浙江大学医学院附属第一医院护理部 杭州市 311100
    2.浙江大学医学院附属第一医院产科 杭州市 311100
    3.浙江大学医学院附属第一医院内镜中心 杭州市 311100
张莉莉：女，本科（硕士在读），副主任护师，副护士长，E-mail：1709103@zju.edu.cn
*黄丽华，E-mail：lihuahuang818@zju.edu.cn

收稿日期: 2025-02-24

  网络出版日期: 2026-02-02

基金资助

浙江省医药卫生科技项目(2022KY157)

收起

Patient-reported outcome measures for patients with post-thrombotic syndrome：a systematic review

  • ZHANG Lili ,
  • ZHANG Yan ,
  • WANG Fangfang ,
  • HUANG Lihua ,
  • YIN Huifang
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  • 1. Department of Nursing， the First Affiliated Hospital，College of Medicine，Zhejiang University， Hangzhou 311100， China
    2. Department of Obstetrics， the First Affiliated Hospital，College of Medicine，Zhejiang University， Hangzhou 311100， China
    3. Endoscopy Center， the First Affiliated Hospital，College of Medicine，Zhejiang University， Hangzhou 311100， China

Received date: 2025-02-24

  Online published: 2026-02-02

Supported by

Zhejiang Provincial Medical and Health Science and Technology Project(2022KY157)

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摘要

目的 评估血栓后综合征患者自我报告工具的测量性能，为临床评估工具的选择提供依据。方法 检索Embase、Medline、Springer Link、Web of Science、PubMed、维普数据库、万方数据库、中国知网等数据库中关于血栓后综合征患者自我报告工具的原始研究，检索时限为建库至2024年12月10日。由2名研究人员独立筛选文献并提取相关资料，基于选择健康测量工具的统一标准（consensus-based standards for the selection of health measurement ins-truments，COSMIN）对评估工具进行评价，若出现分歧，由第3名研究人员决定。结果 共纳入10个评估工具，所有评估工具均存在不同程度的方法学问题。根据COSMIN指南，静脉功能不全生活质量/症状问卷（VEINES-the quality of life/symptom，VEINES-QOL/Sym）和患者报告Villalta量表第2版（the Patient Reported Villalta Scale Version 2，Villalta-PVR2）为A类评估工具，其余量表为B类评估工具。结论 评估工具的选择应取决于具体临床情况，并进一步在不同环境和人群中进行验证，优先推荐Villalta-PVR2量表用于基层筛查，VEINES-QOL/Sym量表用于专科随访，在研究场景的多维探索中，可采用多种测评工具共同协作的形式。

关键词： COSMIN指南; 血栓后综合征; 自我报告工具; 测量性能; 系统评价; 护理

本文引用格式

张莉莉 , 张焱 , 王方方 , 黄丽华 , 尹慧芳 . 血栓后综合征患者结局自我报告工具的系统评价[J]. 中华急危重症护理杂志, 2026 , 7(2) : 223 -230 . DOI: 10.3761/j.issn.2096-7446.2026.02.017

Abstract

Objective To evaluate the measurement performance of patient-reported outcome measures in patients with post-thrombotic syndrome and to provide a basis for the selection of clinical evaluation tools. Methods The original studies on patient-reported outcome measures for patients with post-thrombotic syndrome were searched in databases such as Embase，MEDLINE，Springer Link，Web of science，PubMed，Weipu，Wanfang，and CNKI from inception to December 2024. Two researchers independently screened the literature and extracted relevant data，and the evaluation tools were evaluated based on the consensus-based standards for the selection of health measurement instruments （COSMIN） method，and if there was a disagreement，the third researcher decided. Results A total of 10 evaluation tools was included，and all of them had different degrees of methodological problems. According to COSMIN guidelines，the VEINES-the quality of life/symptom（VEINES-QOL/Sym） and Villalta-PVR2 scales are class A assessment tools，and the rest of the scales are class B assessment tools. Conclusion The choice of assessment tools should be dependent on specific clinical circumstances and further verified in different environments and populations. It is recommended that the Villalta-PVR2 scale be prioritized for primary screening at the grassroots level，and the VEINES-QOL/Sym scale be used for specialized follow-up. In the multi-dimensional exploration of research scenarios，various assessment tools can be adopted in a collaborative manner.

Key words： COSMIN; Post-Thrombotic Syndrome; Patient-Reported Outcome Measure; Measure Performance; Systematic Review; Nursing Care

参考文献

[1] Galanaud JP, Krebs-Drouot L, Genty-Vermorel C, et al. Very long-term risk of moderate-to-severe postthrombotic syndrome after deep vein thrombosis[J]. J Thromb Haemost, 2024, 22(11):3148-3160.
[2] Cosmi B, Stanek A, Kozak M, et al. The post-thrombotic synd-rome-prevention and treatment:VAS-European independent foun-dation in angiology/vascular medicine position paper[J]. Front Cardiovasc Med, 2022, 9:762443.
[3] 鲁乔丹, 王磊, 邓海波, 等. 深静脉血栓形成患者健康相关生活质量评估工具的研究进展[J]. 中华护理杂志, 2022, 57(22):2791-2795.
  Lu QD, Wang L, Deng HB, et al. Research progress of health-related quality of life assessment tools for patients with deep vein thrombosis[J]. Chin J Nurs, 2022, 57(22):2791-2795.
[4] Thieme D, Linnemann B, Mühlberg K, et al. Compression thera-py in acute deep venous thrombosis of the lower limb and for the prevention of post-thrombotic syndrome:a review based on a structured literature search[J]. Dtsch Arztebl Int, 2024, 121(6):188-194.
[5] Snyder DJ, Zilinyi RS, Cohen DJ, et al. Patient-reported out-comes in venous thromboembolism:a systematic review of the literature,current challenges,and ways forward[J]. J Am Heart Assoc, 2023, 12(23):e032146.
[6] 吴倩, 许静, 王铁皓, 等. 患者报告结局在静脉血栓栓塞领域的研究现状[J]. 中国普外基础与临床杂志, 2023, 30(12):1495-1500.
  Wu Q, Xu J, Wang TH, et al. Current research status of patient-reported outcomes in the field of venous thromboembolism[J]. Chin J Bases Clin Gen Surg, 2023, 30(12):1495-1500.
[7] Mason SJ, Catto JWF, Downing A, et al. Evaluating patient-re-ported outcome measures(PROMs) for bladder cancer:a syste-matic review using the COnsensus-based Standards for the selection of health Measurement INstruments(COSMIN) check-list[J]. BJU Int, 2018, 122(5):760-773.
[8] 王海燕, 杜锦萍, 张金换, 等. 白噪声对ICU患者睡眠影响的Meta分析[J]. 中华急危重症护理杂志, 2025, 6(1):57-64.
  Wang HY, Du JP, Zhang JH, et al. Meta-analysis of the effect of white noise on sleep in ICU patients[J]. Chin J Emerg Crit Care Nurs, 2025, 6(1):57-64.
[9] Mokkink LB, Elsman EBM, Terwee CB. COSMIN guideline for systematic reviews of patient-reported outcome measures ver-sion 2.0[J]. Qual Life Res, 2024, 33(11):2929-2939.
[10] Guyatt GH, Oxman AD, Vist GE, et al. GRADE:an emerging consensus on rating quality of evidence and strength of reco-mmendations[J]. BMJ, 2008, 336(7650):924-926.
[11] Kolbach DN, Neumann HM, Prins MH. Definition of the post-thrombotic syndrome,differences between existing classifica-tions[J]. Eur J Vasc Endovasc Surg, 2005, 30(4):404-414.
[12] Tuygun AK, Ketenci B, Günay R, et al. Validity and reliability of VEINES-QOL/Sym questionnaire in chronic venous disor-ders[J]. J Cardiovasc Surg, 2012, 53(3):355-361.
[13] Wik HS, Jacobsen AF, Sandvik L, et al. Prevalence and predi-ctors for post-thrombotic syndrome 3 to 16 years after preg-nancy-related venous thrombosis:a population-based,cross-sectio-nal,case-control study[J]. J Thromb Haemost, 2012, 10(5):840-847.
[14] Utne KK, Ghanima W, Foyn S, et al. Development and valida-tion of a tool for patient reporting of symptoms and signs of the post-thrombotic syndrome[J]. Thromb Haemost, 2016, 115(2):361-367.
[15] Lee A, Gu CS, Vedantham S, et al. Performance of two clini-cal scales to assess quality of life in patients with post-thro-mbotic syndrome[J]. J Vasc Surg Venous Lymphat Disord, 2021, 9(5):1257-1265.e2.
[16] Steiner D, Nopp S, Weber B, et al. The post-VTE functional status scale for assessment of functional limitations in patients with venous thromboembolism:construct validity and responsiveness in a prospective cohort study[J]. Thromb Res, 2023, 221:1-6.
[17] Hofmann A, Deinsberger J, Kienzl P, et al. German translation,cross-cultural adaption and validation of the Venous Clinical Severity and Venous Disability Scores[J]. J Patient Rep Out-comes, 2023, 7(1):28.
[18] Xie XM, Gao J, Bai DX, et al. Assessment tools for stigma in breast cancer patients based on COSMIN guidelines:a syste-matic review[J]. Support Care Cancer, 2023, 32(1):65.
[19] 黄家艺, 邓欣欣, 王汉彬, 等. 公共卫生决策证据质量的Meta流行病学研究[J]. 中国卫生政策研究, 2024, 17(10):76-81.
  Huang JY, Deng XX, Wang HB, et al. The evidence quality of public health decision-making:a meta-epidemiological study[J]. Chin J Health Policy, 2024, 17(10):76-81.
[20] Churruca K, Pomare C, Ellis LA, et al. Patient-reported out-come measures(PROMs):a review of generic and condition-specific measures and a discussion of trends and issues[J]. Health Expect, 2021, 24(4):1015-1024.
[21] 张焱, 张莉莉, 陈建红, 等. 妊娠相关静脉血栓栓塞症评估与预防的最佳证据总结[J]. 中华护理杂志, 2022, 57(14):1765-1771.
  Zhang Y, Zhang LL, Chen JH, et al. Evidence summary for the evaluation and prevention of pregnancy associated venous thromboembolism[J]. Chin J Nurs, 2022, 57(14):1765-1771.
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