ISSN 2097-6046（网络）
ISSN 2096-7446（印刷）
CN 10-1655/R
主管：中国科学技术协会
主办：中华护理学会
中华急危重症护理杂志

中华急危重症护理杂志 ›› 2026, Vol. 7 ›› Issue (3): 312-315.doi: 10.3761/j.issn.2096-7446.2026.03.009

• 急症护理研究 • 上一篇    下一篇

兰尼碱受体2基因变异相关儿茶酚胺敏感性多形性室性心动过速患儿的护理

沈丹军1(), 诸纪华2, 徐红贞2, 冯佳艳3, 郑虹1, 叶飞亚1, 盛美君1,*()   

  1. 1 国家儿童健康与疾病临床医学研究中心/浙江大学医学院附属儿童医院外科重症监护室 杭州市 310052
    2 国家儿童健康与疾病临床医学研究中心/浙江大学医学院附属儿童医院护理部 杭州市 310052
    3 国家儿童健康与疾病临床医学研究中心/浙江大学医学院附属儿童医院国际医学部 杭州市 310052
  • 收稿日期:2025-08-25 出版日期:2026-03-10 发布日期:2026-03-02
  • 通讯作者: *盛美君，E-mail：smj512@zju.edu.cn
  • 作者简介:沈丹军：男，本科（硕士在读），护师，E-mail：6518111@zju.edu.cn

Nursing care of a child with ryanodine receptor 2 gene variant-related catecholaminergic polymorphic ventricular tachycardia

SHEN Danjun1(), ZHU Jihua2, XU Hongzhen2, FENG Jiayan3, ZHENG Hong1, YE Feiya1, SHENG Meijun1,*()   

  1. 1 Surgical Intensive Care Unit， Children’s Hospital Zhejiang University School of Medicine， Hangzhou 310052， China
    2 Nursing Department， Children’s Hospital Zhejiang University School of Medicine， Hangzhou 310052， China
    3 International Medical Department， Children’s Hospital Zhejiang University School of Medicine， Hangzhou 310052， China
  • Received:2025-08-25 Online:2026-03-10 Published:2026-03-02
  • Contact: *SHENG Meijun，E-mail：smj512@zju.edu.cn

RichHTML

PDF下载

摘要：

总结1例兰尼碱受体2基因变异相关儿茶酚胺敏感性多形性室性心动过速并发心搏骤停患儿的护理体会。针对该患儿缺血缺氧时间长、病情进展迅速、反复恶性心律失常及高敏感性情绪反应等护理难点，快速启动个体化目标温度管理，实施体外膜肺氧合联合俯卧位通气治疗，及早识别恶性心律失常，迅速激活应急响应系统，采取多维度情绪刺激规避策略，减少恶性心律失常事件发生，同时早期开展渐进性运动康复。经过31 d精心护理，患儿顺利转外院行康复治疗，随访近6个月，未再发生恶性心律失常。

关键词: 兰尼碱受体2, 遗传变异, 心动过速, 室性, 儿科护理, 危重病护理

Abstract:

To summarize the nursing experience of a child with ryanodine receptor 2 gene variant-related catecholaminergic polymorphic ventricular tachycardia complicated with cardiac arrest. Given the nursing challenges of prolonged ischemic hypoxia，rapid disease progression，recurrent malignant arrhythmia，and highly sensitive emotional stimuli in this pediatric patient，we implemented rapid initiation of individualized high-quality targeted temperature management，conducted extracorporeal membrane oxygenation combined with prone ventilation therapy，promptly identified malignant arrhythmia，quickly activated the emergency response system，adopted multidimensional emotional stimulus avoidance strategies to reduce malignant arrhythmia episodes，while initiating progressive motor rehabilitation early. After 31 days of meticulous nursing，the child was successfully transferred to another hospital for rehabilitation therapy. During the 6-month follow-up period，no further malignant arrhythmia events occurred.

Key words: Ryanodine Receptor 2, Genetic Variation, Tachycardia, Ventricular, Pediatric Nursing, Critical Care Nursing