Chinese Journal of Emergency and Critical Care Nursing >
Dynamic blood pressure changes and their association with postoperative complications after revascularization surgery for moyamoya disease
Received date: 2026-02-11
Online published: 2026-08-31
Supported by
Zhejiang Province Medical and Health Science and Technology Project(2023KY750)
Objective To analyze the association of dynamic blood pressure changes and circadian rhythm characteristics within 72 hours after revascularization surgery with postoperative complications in patients with moyamoya disease,and to provide a basis for the precise management of postoperative blood pressure. Methods Clinical data of 401 patients with moyamoya disease who underwent revascularization surgery at a tertiary Grade A hospital in Zhejiang Province from January 2020 to January 2024 were retrospectively analyzed. The collected data included general patient information and hourly systolic and diastolic blood pressure measurements within 72 hours after surgery. Blood pressure parameters were calculated for three postoperative time intervals:0-24 h,25-48 h,and 49-72 h. Based on the change trend of the nocturnal blood pressure decline rate over three consecutive days,the circadian rhythm patterns of systolic blood pressure were classified into three levels:fluctuation,deterioration pattern,and persistent deterioration. Multivariable logistic regression was performed to examine the association between blood pressure variability indicators and postoperative complications within 7 days after surgery. Results The incidence of postoperative complications was 26.93%(108/401). Multivariable logistic regression analysis showed that deterioration of systolic circadian rhythm(aOR=1.366,95%CI:1.025-1.821,P=0.033) and elevated mean systolic blood pressure within 0~48 hours after surgery(aOR=1.611,95%CI:1.245-2.085,P<0.001) were independent risk factors for postoperative complications. Each one-standard-deviation increase of 11.1 mmHg in mean systolic blood pressure(123.4 mmHg,1 mmHg=0.133 kPa) was associated with a 61.1% increase in the risk of complications. Conclusion The first 48 hours following revascularization surgery for moyamoya disease represent a pivotal time window. During this period,stringent blood pressure control should be exercised,and clinicians should be alert to potential dynamic deterioration of the circadian rhythm.
GU Qiuping , ZHANG Weiwei , XU Gaowei , WANG Jingyi , TANG Xiaolan , YUAN Yuan . Dynamic blood pressure changes and their association with postoperative complications after revascularization surgery for moyamoya disease[J]. Chinese Journal of Emergency and Critical Care Nursing, 2026 , 7(9) : 1029 -1035 . DOI: 10.3761/j.issn.2096-7446.2026.09.001
| [1] | Cheng XY, Cao Y, Duan JB, et al. Moyamoya disease:epidemiology,clinical features,pathogenesis,diagnosis and therapeutic interventions[J]. Mol Biomed, 2025, 6(1):76. |
| [2] | Nguyen VN, Motiwala M, Elarjani T, et al. Direct,indirect,and combined extracranial-to-intracranial bypass for adult moyamoya disease:an updated systematic review and meta-analysis[J]. Stroke, 2022, 53(12):3572-3582. |
| [3] | 陈浩, 王毅, 吴凌云, 等. 颅外-颅内联合脑血运重建术治疗出血型烟雾病的远期临床预后及脑灌注状态研究[J]. 中国脑血管病杂志, 2023, 20(9):587-596. |
| Chen H, Wang Y, Wu LY, et al. Research of long-term clinical prognosis and cerebral perfusion of hemorrhagic Moyamoya disease after combined extra-intracranial bypass[J]. Chin J Cere-brovasc Dis, 2023, 20(9):587-596. | |
| [4] | Aziz Rizk A, Nijs K, Di Donato AT, et al. Epidemiology of post-craniotomy hypertension and its association with adverse outcome(s):a systematic review and meta-analysis[J]. J Neurosurg Anesthesiol, 2025, 37(4):350-360. |
| [5] | Fujimura M, Ito M, Uchino H, et al. Efficacy and safety of combined revascularization surgery for moyamoya disease:standard procedure and perioperative management[C]// Trends in the Treatment of Cerebrovascular Diseases. Cham:Springer,2025:99-104. |
| [6] | 桂金敏, 薛锐, 李娜, 等. 个体化血压及液体管理对烟雾病脑血管重建术后过度灌注综合征的影响[J]. 中国卒中杂志, 2022, 17(12):1350-1354. |
| Gui JM, Xue R, Li N, et al. Individualized management of blood pressure and liquid control for moyamoya patients with hyperperfusion syndrome after extracranial-intracranial bypass[J]. Chin J Stroke, 2022, 17(12):1350-1354. | |
| [7] | Eilertsen RK, Midtb? H, Nawaz B, et al. Associations of short-term blood pressure variability with presence and progression of organ damage over five years in ischaemic stroke survivors:the Norwegian Stroke in the Young Study[J]. Blood Press, 2025, 34(1):2521523. |
| [8] | 尹梦鑫, 段春苗, 杨海华. 急性缺血性卒中患者再灌注治疗后血压变异性与功能预后的相关性研究[J]. 中国卒中杂志, 2025, 20(10):1261-1269. |
| Yin MX, Duan CM, Yang HH. Correlation between blood pressure variability and functional outcomes in patients with acute ischemic stroke after reperfusion therapy[J]. Chin J Stroke, 2025, 20(10):1261-1269. | |
| [9] | Se?kin ?, ünlü S, Yal??n MR. The hidden role of left atrial strain:insights into end-organ damage in dipper and nondipper hypertension[J]. J Hum Hypertens, 2025, 39(6):425-431. |
| [10] | Kuroda S, Fujimura M, Takahashi J, 等. 烟雾病诊断标准:2021修订版[J]. 中国脑血管病杂志, 2023, 20(12):862-865. |
| Kuroda S, Fujimura M, Takahashi J, et al. Diagnostic criteria for Moyamoya disease:2021 revised version[J]. Chin J Cerebrovasc Dis, 2023, 20(12):862-865. | |
| [11] | Dhiman P, Ma J, Qi C, et al. Sample size requirements are not being considered in studies developing prediction models for binary outcomes:a systematic review[J]. BMC Med Res Methodol, 2023, 23(1):188. |
| [12] | Miller R, Anikpezie N, Hoffman H, et al. Demographic disparities in the incidence of moyamoya angiopathy in the United States[J]. Neurology, 2025, 105(5):e214013. |
| [13] | Ali Momeni M, Esmaeilpur Abianeh F, Amini MJ, et al. Incidence of cerebral hyperperfusion syndrome following revascularization surgery in moyamoya patients:a systematic review and meta-analysis[J]. Neurosurg Rev, 2025, 49(1):71. |
| [14] | Musmar B, Roy JM, Abdalrazeq H, et al. The impact of hypertension on clinical outcomes in moyamoya disease:a multicenter,propensity score-matched analysis[J]. Acta Neurochir, 2024, 166(1):366. |
| [15] | Ishiyama Y, Hoshide S, Kario K. Systemic hemodynamic athero-thrombotic syndrome:from hypothesis to evidence[J]. Hypertens Res, 2024, 47(3):579-585. |
| [16] | Kim JH, Hong N, Kim H, et al. Autoregulatory dysfunction in adult Moyamoya disease with cerebral hyperperfusion syndrome after bypass surgery[J]. Sci Rep, 2024, 14(1):26451. |
| [17] | 中华医学会神经外科学分会. 烟雾病和烟雾综合征诊断与治疗中国专家共识(2024版)[J]. 中华神经外科杂志, 2024, 40(3):220-229. |
| Chinese Neurosurgical Society. Chinese expert consensus on the diagnosis and treatment of moyamoya disease and moyamoya syndrome(2024 edition)[J]. Chin J Neurosurg, 2024, 40(3):220-229. | |
| [18] | Eckert M, Bhakta N, Cohen SA, et al. Perioperative practices in moyamoya syndrome revascularization:an international transdisciplinary survey[J]. Stroke Vasc Interv Neurol, 2023, 3(2):e000521. |
| [19] | Hermida RC, Crespo JJ, Domínguez-Sardi?a M, et al. Bedtime hypertension treatment improves cardiovascular risk reduction:the Hygia Chronotherapy Trial[J]. Eur Heart J, 2020, 41(48):4565-4576. |
| [20] | Chen M, Liu S, Wang H, et al. A novel composite risk model based on blood pressure variability and circadian rhythm for predicting postoperative complications[J]. Critical Care Medi-cine, 2023, 51(3):e245-e253. |
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