Abstract: Objectives To compare the effects of volume-based feeding and rate-based feeding for critical pa- tients.Methods 56 patients in ICU were recruited from February 2018 to February 2019. They were divided into the control group （n=28） and the experimental group （n=28） by random number table method. The patients in the experimental group were given volume-based feeding and control group were given rate-based feeding. We record the nutritional indicators and incidence of complications. Results After 7 days of enteral nutrition treatment，there were statistically significant differences between the two groups in actual daily caloric intake and pre-albumin index （P<0.05）. Conclusion Volume-based feeding can effectively improve nutritional status and immune function of patients in ICU.

Key words: Enteral Nutrition, Intensive Care Units, Nursing Protocols