Abstract: Objective To develop a knowledge，attitude and practice（KAP） questionnaire about intensive care unit （ICU） nurses’ target temperature management（TTM） for patients with severe traumatic brain injury（STBI），and to test its reliability and validity. Methods Using the theory of KAP as the framework，a pool of questionnaire items was initially constructed through literature analysis and group discussion，and then the first draft of the questionnaire was determined by Delphi method and pre-survey. 240 ICU nurses from four hospitals in Gansu Province were selected for the questionnaire survey using convenience sampling method to test the reliability and validity of the questionnaire in October 2022. Results The KAP questionnaire about ICU nurses’ TTM for patients with STBI contained 3 dimensions with 32 items. The overall content validity index of the questionnaire was 0.955，and the content validity index of the items was 0.800~1.000. Exploratory factor analysis extracted 4 main factors with a cumulative variance contribution rate of 58.889% . The overall Cronbach’s α coefficient of the questionnaire was 0.862，the retest reliability coefficient was 0.890. The Cronbach’s α coefficients of the dimensions of knowledge，attitude，and practice were 0.713，0.925，and 0.924 respectively，and the retest reliability coefficients was 0.801，0.943 and 0.950 respectively. Conclusion The KAP questionnaire about ICU nurses’ TTM for patients with STBI has good reliability and validity and can be used as an assessment tool to measure ICU nurses’ KAP of TTM for patients with STBI.

Key words: Intensive Care Units, Nurses, Craniocerebral Trauma, Target Temperature Management, Health Knowledge, Attitude, Practice, Reliability, Validity