总结10例口腔颌面部间隙感染继发下行坏死性纵隔炎患者的护理经验。 针对该组患者发生呼吸道梗阻、纵隔感染导致呼吸不畅、间隙感染术后置入不同引流装置的护理难点、术后严重并发症护理等问题，采取针对性气道管理，胸腔穿刺治疗后的管道管理，3种不同引流装置的个性化护理，重视患者主诉、动态评估患者术后并发症风险、 及时判断并处理患者糖尿病酮症酸中毒、静脉血栓栓塞症及消化道出血等并发症。 经积极对症治疗和护理，该组患者临床症状明显好转，住院第11～53天出院。

The nursing experience of 10 cases of descending necrotizing mediastinitis secondary to oral and maxillofacial space infection was summarized. In terms of problems such as airway obstruction，mediastinal infection leading to dyspnea，postoperative placement of different drainage devices after interstitial infection，and postoperative serious complications in this group of patients，we adopted targeted airway management，postoperative pipeline management after thoracentesis treatment，personalized care of three different drainage devices and focused on patient complaints，implemented dynamic assessment of the risks of postoperative complications，timely judged and treated complications such as diabetic ketoacidosis，venous thromboembolism and gastrointestinal bleeding. After active treatment and nursing，the patients in this group improved significantly，and they were discharged from the hospital within 11 to 53 days.