Objective To search,evaluate,and integrate evidence on hyperglycemia management in ICU enteral nutrition patients and summarize the best evidence. Methods We searched European Society for Parenteral and Enteral Nutrition Network,American Society for Parenteral and Enteral Nutrition Network,Joanna Briggs Institute （JBI） Evidence-based Health Care Database,Cochrane Library,OVID Evidence-Based Database,UpToDate,PubMed,Embase,CINAHL,Wanfang Database,VIP Chinese Scientific and Technical Journal Database,CNKI and SinoMed Database for clinical practice guidelines,systematic review,original studies and other evidence. The literature quality and evidence level were evaluated using the literature evaluation criteria and evidence grading system of Australia JBI Evidence-based Health Care Center. Results A total of 13 literatures were included,and 19 best evidences were collected from 5 aspects：nutrition screening and evaluation,routes and formulation selection of enteral nutrition,use of enteral nutrition pump and infusion speed control,blood glucose monitoring,and hyperglycemia management. Conclusion It is suggested that clinical departments should comprehensively evaluate the environment and policies of medical institutions,as well as the promotion and obstacle factors of evidence application when applying evidence. And the clinical departments should implement multidisciplinary cooperation of blood glucose management model in enteral nutrition patients,standardize enteral nutrition and blood glucose clinical practice,strengthen the training and communication for collaboration of medical staff,so as to reduce patients' glucose safely and stably,improve nutritional status and quality of life.
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