目的 分析急诊骨髓腔输液患者液体外渗的危险因素,为骨髓腔输液患者液体外渗的早期评估和筛查提供依据。方法 回顾性分析浙江省3所医院2017年1月—2020年12月358例骨髓腔输液患者的临床资料,以是否发生液体外渗分为两组,对比两组临床指标的差异,采用Logistic回归模型分析骨髓腔置管患者液体外渗的独立危险因素。结果 参与调查的358例患者中15例（4.18%）发生液体外渗。Logistic回归分析显示,患者BMI、疼痛等级、转运次数、骨髓腔置管留置时间是急诊骨髓腔输液患者发生液体外渗的独立危险因素,置管部位、既往置管经验是其独立保护因素（P<0.05）。结论 临床工作中应加强关注肥胖、置管在肱骨部位的躁动且疼痛明显患者,并减少搬运,安排有资质人员指导抢救。
Objective To analyze the risk factors of extravasation in emergency patients with intraosseous infusion,to provide early assessment and screening of extravasation in patients with intraosseous infusion. Methods We retrospectively analyzed the data of 358 patients with bone marrow cavity infusion in three hospitals in Zhejiang Province from January 2017 and December 2020. The patients were divided into two groups according to whether there was any extravasation. Compared the differences of clinical indicators in two groups,analyzed independent factors of extravasation in patients with intraosseous infusion by Logistic regression model. Results A total of 15 patients（4.18%） were found to have extravasation. Multivariate Logistic regression analysis showed that Body Mass Index（BMI）,pain grade,transport times,intraosseous retention time were independent risk factors for extravasation. The position of catheterization and previous experience of catheterization were independent protective factors（P< 0.05）. Conclusion Nurses should pay attention to obese patients, and patients with intraosseous tube in the humeral site and obvious pain, and reduce moving the patients,try to arrange experienced nurses to guide the rescue.
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