ISSN 2097-6046(网络)
ISSN 2096-7446(印刷)
CN 10-1655/R
主管:中国科学技术协会
主办:中华护理学会
论著

院前家庭肺康复在肺癌合并慢性阻塞性肺疾病患者中的应用研究

  • 韩娜菲 ,
  • 贺红 ,
  • 金尧娟 ,
  • 胡晓敏 ,
  • 刘锦凯 ,
  • 沈涛
展开
  • 310009 杭州市 浙江大学医学院附属第二医院胸外科(韩娜菲,贺红,金尧娟,胡晓敏),门诊(刘锦凯),康复科(沈涛)
韩娜菲:女,本科,副主任护师,E-mail:2505117@zju.edu.cn

收稿日期: 2021-06-14

  网络出版日期: 2022-01-17

基金资助

浙江省教育厅课题(Y201941221)

Application of prehospital home-based pulmonary rehabilitation in patients with lung cancer combined with chronic obstructive pulmonary disease

  • HAN Nafei ,
  • HE Hong ,
  • JIN Yaojuan ,
  • HU Xiaomin ,
  • LIU Jinkai ,
  • SHEN Tao
Expand
  • Department of Thoracic Surgery, the Second Affiliated Hospital of the Zhejiang University School of Medicine, Hangzhou, 310009, China

Received date: 2021-06-14

  Online published: 2022-01-17

摘要

目的 探讨院前家庭肺康复在肺癌合并慢性阻塞性肺疾病患者加速康复中的应用效果。方法 采用便利抽样法,将2019年12月—2020年12月收治的130例肺癌合并慢性阻塞性肺疾病患者按随机数字表法分为试验组和对照组。试验组在加速康复管理方案的基础上应用院前家庭肺康复方案,对照组给予加速康复管理方案。两组入院后第2天行手术治疗,全程运用加速康复方案。比较两组肺功能、6 min步行试验、峰流速、自我管理分值、术后并发症发生率、抗生素使用时间、住院时间和住院费用的差异。结果 实施过程中试验组脱落2例,最终试验组完成67例、对照组61例。干预后试验组中度慢性阻塞性肺疾病患者术后抗生素使用时间缩短(Z=-2.408,P=0.016);每日峰流速均值显著增加(F=152.870,P<0.001);自我管理总分提高(Z=-6.795,P<0.001);术后并发症发生率、住院时间、住院费用降低(P<0.05);试验组中度慢性阻塞性肺疾病患者术前肺功能提高(P<0.05);6 min步行试验结果比较,差异无统计学意义(P>0.05)。结论 院前家庭肺康复训练有助于改善患者肺功能,提高峰流速,提升患者的自我管理能力,减少抗生素使用时间;在肺癌合并中度慢性阻塞性肺疾病患者中效果更为显著,有助于降低术后并发症的发生率,缩短住院时间,降低住院费用。

本文引用格式

韩娜菲 , 贺红 , 金尧娟 , 胡晓敏 , 刘锦凯 , 沈涛 . 院前家庭肺康复在肺癌合并慢性阻塞性肺疾病患者中的应用研究[J]. 中华急危重症护理杂志, 2022 , 3(1) : 16 -23 . DOI: 10.3761/j.issn.2096-7446.2022.01.002

Abstract

Objective To explore the effect of prehospital home-based pulmonary rehabilitation training on enhanced recovery after surgery(ERAS) in patients with lung cancer combined with chronic obstructive pulmonary disease(COPD). Methods From December 2019 to December 2020,130 patients with lung cancer combined with COPD were divided into experimental group and control group according to random number table. The experimental group received prehospital pulmonary rehabilitation training intervention on the basis of the ERAS program,and the control group was provided with the ERAS program. The patients received surgery at the second day after admission and the ERAS program was performed through the entire process. Lung function,6-minute walk test,peak flow rate,self-management score,incidence of postoperative complications,duration of antibiotic use,length of hospital stay,and hospitalization cost were compared between the two groups. Results In the process of implementation,2 cases were dropped out in the experimental group. Finally we had 67 cases in the experimental group and 61 cases in the control group. Compared with the control group,the duration of antibiotic use in the experimental group for patients with moderate COPD after surgery was shorter(Z=-2.408,P=0.016). The mean daily peak velocity was significantly increased(F=152.870,P<0.001). The total score of self-management was increased(Z=-6.795,P<0.001). The incidence of postoperative complications,length of hospital stay and hospitalization cost were decreased(P<0.05). Preoperative lung function of patients with moderate COPD was improved after intervention and the difference was statistically significant(P<0.05). However the difference in the 6-minute walk test was not statistically significant(P>0.05). Conclusion Prehospital home-based pulmonary rehabilitation training can improve patients' lung function,increase peak flow rate,improve patient self-management ability and reduce antibiotic use time. It is more effective in patients with lung cancer and moderate COPD. Furthermore,it can also help reduce the incidence of postoperative complications,shorten the length of hospital stay,thereby reduce the cost of hospitalization.

参考文献

[1] Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015[J]. CA Cancer J Clin,2016,66(2):115-132.
[2] Mouronte-Roibás C,Leiro-Fernández V,Fernández-Villar A,et al.COPD,emphysema and the onset of lung cancer. A syste-matic review[J]. Cancer Lett,2016,382(2):240-244.
[3] Franssen FM,Spruit MA.Pulmonary rehabilitation in Australia and New Zealand:from guidelines to personalized treatment[J]. Respirology,2017,22(4):622-623.
[4] Bolton CE,Bevan-Smith EF,Blakey JD,et al.British Thoracic Society guideline on pulmonary rehabilitation in adults[J]. Thorax,2013,68(Suppl 2):1-30.
[5] Cavalheri V,Granger C. Preoperative exercise training for patients with non-small cell lung cancer[J]. Cochrane Database Syst Rev,2017,6:CD012020.
[6] Pradella CO,Belmonte GM,Maia MN,et al.Home-based pulmonary rehabilitation for subjects with COPD:a randomized study[J]. Respir Care,2015,60(4):526-532.
[7] Vogelmeier CF,Criner GJ,Martinez FJ,et al.Global strategy for the diagnosis,management,and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary[J]. Am J Respir Crit Care Med,2017,195(5):557-582.
[8] Laurent H,Galvaing G,Thivat E,et al.Effect of an intensive 3-week preoperative home rehabilitation programme in patients with chronic obstructive pulmonary disease eligible for lung cancer surgery:a multicentre randomised controlled trial[J]. BMJ Open,2017,7(11):e017307.
[9] 那荣瑞,金健,雷跃昌,等. 6分钟步行试验在胸外科应用的临床价值和现状[J]. 中国胸心血管外科临床杂志,2017,24(4):310-314.
Na RR,Jin J,Lei YC,et al.Clinical value and status of six-minute walk test in thoracic surgery[J]. Chin J Clin Thorac Cardiovasc Surg,2017,24(4):310-314.
[10] 刘又宁. 呼吸内科学高级教程[M]. 北京:中华医学电子音像出版社,2016.
Liu YN.Respiratory medicine[M]. Beijing:China Medical Electronic Audio-visual Publishing Press,2016.
[11] 孟胜蓝,杨帆,戴富强,等. 术前短期高强度肺康复训练对肺癌合并COPD患者围手术期并发症的影响[J]. 中国肺癌杂志,2018,21(11):841-848.
Meng SL,Yang F,Dai FQ,et al.Effect of a high intensive preoperative rehabilitation on the perioperative complications in patients with chronic obstructive pulmonary disease eligible for lung cancer surgery[J]. Chin J Lung Cancer,2018,21(11):841-848.
[12] 张彩虹. 慢性阻塞性肺疾病患者自我管理水平及影响因素研究[D]. 长沙:中南大学,2009.
Zhang CH.Study of self-management level and influencing factors in patients with chronic obstructive pulmonary disease[D]. Changsha:Central South University,2009.
[13] Huang J,Lai YT,Zhou XD,et al.Short-term high-intensity rehabilitation in radically treated lung cancer:a three-armed randomized controlled trial[J]. J Thorac Dis,2017,9(7):1919-1929.
[14] Zhou K,Su JH,Lai YT,et al.Short-term inpatient-based high-intensive pulmonary rehabilitation for lung cancer patients:is it feasible and effective?[J]. J Thorac Dis,2017,9(11):4486-4493.
[15] Agostini P,Cieslik H,Rathinam S,et al.Postoperative pulmonary complications following thoracic surgery:are there any modifiable risk factors?[J]. Thorax,2010,65(9):815-818.
[16] Gupta H,Ramanan B,Gupta PK,et al.Impact of COPD on postoperative outcomes:results from a national database[J]. Chest,2013,143(6):1599-1606.
[17] Wang C,Xu JY,Yang L,et al.Prevalence and risk factors of chronic obstructive pulmonary disease in China(the China Pulmonary Health[CPH] study):a national cross-sectional study[J]. Lancet,2018,391(10131):1706-1717.
[18] 刘青,陈亚红,王仲,等. 北京市社区全科医生对慢性阻塞性肺疾病的认知现状及影响因素分析[J]. 中国全科医学,2021,24(8):982-988.
Liu Q,Chen YH,Wang Z,et al.Analysis of the status quo and influencing factors of Beijing community general practitioners on chronic obstructive pulmonary disease[J]. Chin Gen Pract,2021,24(8):982-988.
[19] 谢冬,陈昶,朱余明,等. 日间手术及加速康复外科用于早期肺癌微创外科517例的探索与实践[J]. 中国胸心血管外科临床杂志,2021.1(1):1-7.
Xie D,Chen C,Zhu YM,et al.The management of day surgery in minimally invasive surgery for early-stage lung cancer by enhanced recovery after surgery[J]. Chin J Clin Thorac Cardiov Surg,2021,1(1):1-7.
[20] Rispoli M,Salvi R,Cennamo A,et al.Effectiveness of home-based preoperative pulmonary rehabilitation in COPD patients undergoing lung cancer resection[J]. Tumori,2020:300891619900808.
[21] Coats V,Maltais F,Simard S,et al.Feasibility and effectiveness of a home-based exercise training program before lung resection surgery[J]. Can Respir J,2013,20(2):e10-e16.
文章导航

/