Translation and validation of the Chinese version of the Newcastle Laryngeal Hypersensitivity Questionnaire
Received date: 2025-07-24
Online published: 2026-06-02
目的 对纽卡斯尔喉部高敏感问卷（Newcastle Laryngeal Hypersensitivity Questionnaire，NLHQ）进行汉化，并检验中文版NLHQ在重症机械通气患者中的信效度。 方法 征得原作者同意后，按Brislin翻译模型对NLHQ进行汉化，选择2023年7月—2025年1月苏州市某三级甲等医院收治的285例重症机械通气患者作为调查对象，验证问卷的信效度。 结果 中文版NLHQ共3个维度、13个条目，Cronbach’s α系数为0.853，分半信度为0.827，内容效度指数（sale-content validity index/average，S-CVI/Ave）为0.973；探索性因子分析提取出3个公因子，累计方差贡献率为67.67%，验证性因子分析显示模型拟合良好；效标效度显示，中文版NLHQ评分与中文版Hull气道反流问卷（Hull Airway Reflux Questionnaire，HARQ）评分呈负相关（r<0，P<0.05）；绘制受试者操作特征曲线（receiver operating characteristic curve，ROC）发现，NLHQ评分预测重症机械通气患者拔管失败的曲线下面积（area under curve，AUC）为0.895（95%CI：0.844~0.946），最佳截断值为39分。 结论 中文版NLHQ具有良好的信效度，可作为评估中国重症机械通气患者喉部不适感的工具，且对拔管失败具有一定的预测价值。
关键词： 纽卡斯尔喉部高敏感问卷; 重症机械通气; 汉化; 信度; 效度
梅高鹏 , 刘军 , 杨建兰 . 纽卡斯尔喉部高敏感性问卷的汉化及信效度检验[J]. 中华急危重症护理杂志, 2026 , 7(6) : 717 -724 . DOI: 10.3761/j.issn.2096-7446.2026.06.015
Objective To translate the Newcastle Laryngeal Hypersensitivity Questionnaire（NLHQ） into Chinese and validate the reliability and validity of the Chinese version of the NLHQ scale in critically ill mechanically ventilated patients. Methods After obtaining permission from the original author，the NLHQ was translated using the Brislin translation model. A total of 285 critically ill mechanically ventilated patients admitted to a tertiary hospital in Suzhou between July 2023 and January 2025 were selected to validate the reliability and validity of the questionnaire. Results The Chinese version of the NLHQ scale consisted of 3 dimensions and 13 items. The Cronbach’s α coefficient was 0.853，the split-half reliability was 0.827，and the content validity index （S-CVI/Ave） was 0.973. Exploratory factor analysis extracted 3 common factors，with a cumulative variance contribution rate of 67.67%. Confirmatory factor analysis showed good model fit. Criterion validity indicated that the Chinese version of the NLHQ scale score was negatively correlated with the Chinese version of the Hull Airway Reflux Questionnaire （HARQ） scale score（r<0，P<0.05）. The ROC curve analysis revealed that the AUC of the NLHQ score for predicting extubation failure in critically ill mechanically ventilated patients was 0.895（95%CI：0.844-0.946），with an optimal cutoff value of 39 points. Conclusion The Chinese version of the NLHQ scale demonstrates good reliability and validity and can be used as a tool to assess laryngeal discomfort in critically ill mechanically ventilated patients in China. It also has certain predictive value for extubation failure.
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