总结1例家族性肥厚型心肌病合并肝衰竭患者接受心肝同期联合移植的护理体会。针对围手术期凝血功能的动态转变、多器官间的交互影响、免疫抑制管理，以及移植器官功能延迟恢复等复杂问题，采取了凝血功能观察与继发性神经系统并发症护理、体外循环—体外膜肺氧合过渡管理、最小有效潮气量的精细化滴定与监测、移植器官功能延迟恢复的管理、免疫抑制平衡与监护、以腹内压为导向的营养支持等措施。经过34 d的精细化护理，患者成功转出ICU并康复出院。

To summarize the nursing experience of a patient with familial hypertrophic cardiomyopathy complicated with liver failure undergoing combined heart-liver transplantation. To address complex challenges such as dynamic changes in perioperative coagulation function，inter-organ interactions，immunosuppression management，and delayed functional recovery of combined transplanted organs，the following measures were implemented：coagulation function monitoring and nursing care for secondary neurological complications，management of transition from extracorporeal circulation to extracorporeal membrane oxygenation，precise titration and monitoring of minimal effective tidal volume，management of delayed functional recovery in transplanted organs，balance and meticulous monitoring of immunosuppression，and precision nutritional support guided by intra-abdominal pressure. After 34 days of intensive care，the patient was successfully transferred out of the ICU and discharged after recovery.