目的 探讨腹式呼吸联合抗阻运动方案在ICU机械通气患者中的应用效果。方法 选取2023年9月—2024年9月入住福建省南平市2所三级甲等医院综合ICU行机械通气治疗的192例患者为研究对象，采用简单随机分组方法，分为腹式呼吸联合抗阻运动组、早期渐进式活动组、常规活动组，观察3组研究对象谵妄发生率、焦虑抑郁评分、睡眠质量评分、ICU机械通气时间、ICU住院时间等临床结局指标。结果 3组谵妄发生率比较，腹式呼吸联合抗阻运动组<早期渐进式活动组<常规活动组，差异均具有统计学意义（P<0.05）；ICU住院期间焦虑抑郁评分、睡眠质量评分比较，腹式呼吸联合抗阻运动组和早期渐进式活动组低于常规活动组，差异均有统计学意义（P<0.05）；3组ICU机械通气时长、ICU住院时长比较，腹式呼吸联合抗阻运动组<早期渐进式活动组<常规活动组，差异均有统计学意义（P<0.05）。结论 腹式呼吸联合抗阻运动可降低ICU机械通气患者谵妄发生率、改善危重患者焦虑抑郁情绪、提高危重患者睡眠质量、缩短机械通气时长及ICU住院时长，有利于改善危重患者临床结局。

Objective To explore the application effects of the combined limb and abdominal breathing resistance exercise program in ICU patients with mechanical ventilation. Methods From September 2023 to September 2024，192 patients who underwent mechanical ventilation treatment in the general ICU of two tertiary grade A hospitals in Nanping City，Fujian Province，were selected as the research subjects. Using the simple random grouping method，they were divided into the combined limb and abdominal breathing resistance exercise group，the early progressive activity group，and the conventional activity group. The incidence of delirium，anxiety and depression score，sleep quality score，ICU mechanical ventilation time，and ICU hospitalization time of research subjects in the three groups were observed. Results Comparison of the incidence of delirium among the three groups of research subjects showed that the incidence in combined limb and abdominal breathing resistance exercise group was lower than the early progressive activity group and the conventional activity group（P<0.05）. Comparison of anxiety and depression scores and sleep quality scores during ICU stay showed that the combined limb and abdominal breathing resistance exercise group and the early progressive activity group were lower than the conventional activity group（P<0.05）. And the lengths of mechanical ventilation and ICU hospitalization in the three groups were compared，the combined limb and abdominal breathing resistance exercise group was shorter than the early progressive activity group and the conventional activity group，and the differences were statistically significant（P<0.05）. Conclusion The combination of limb and abdominal breathing resistance exercise can reduce the incidence of delirium in ICU patients with mechanical ventilation，improve the anxiety and depression of critically ill patients，improve the sleep quality of critically ill patients，shorten the duration of mechanical ventilation and ICU hospitalization，and is conducive to improving the clinical outcomes of critically ill patients.