总结1例甲醇中毒致顽固性低钾血症患者的护理体会。针对该患者毒物接触史不明，存在顽固性低钾血症、视神经损伤及情绪障碍等多重复杂情况，运用评判性思维深入追问病史，结合临床表现及毒物检测明确甲醇中毒诊断；制订并执行个体化精准补钾方案，实施血液灌流并动态纠正代谢性酸中毒；建立多模态监护预警体系，严防心律失常等并发症；采用中西医药结合治疗促进视神经功能恢复；实施结构化心理支持以缓解焦虑抑郁。经过精心治疗和护理，患者病情稳定出院。出院1个月随访，患者预后良好。

To summarize the nursing experience of a patient with refractory hypokalemia caused by methanol poisoning. The patient ’s history of toxic exposure was unknown，and there were multiple complex conditions such as refractory hypokalemia，optic nerve injury and emotional disorders. Nursing points included the use of critical thinking for in-depth inquiry of medical history，combination of clinical manifestations and poison detection to determine the diagnosis of methanol poisoning，formulating and implementing individualized precise potassium supplementation program，and implementing hemoperfusion to dynamically correct metabolic acidosis，establishing a multi-modal monitoring and early warning system to prevent complications such as arrhythmia，the combination of Chinese and Western medicine and specialist nursing intervention to promote the recovery of optic nerve function，implementing structured psychological support to relieve anxiety and depression. After careful treatment and nursing，the patient was in stable condition and discharged. The patient was followed up for 1 month after discharge，and the prognosis was good.