目的 识别急性冠脉综合征（acute coronary syndrome，ACS）患者经皮冠状动脉介入治疗（percutaneous coronary intervention，PCI）术后症状负担的潜在剖面，分析不同剖面的影响因素，为实施分层护理管理提供依据。 方法 采用便利抽样法，选取2024年11月—2025年8月重庆市某三级甲等医院接受PCI治疗的261例ACS患者作为研究对象。采用一般资料调查表、心脏症状调查量表、西雅图心绞痛量表进行调查，采用潜在剖面分析识别症状负担的潜在类别，采用无序多分类Logistic回归分析探讨不同潜在剖面的影响因素。 结果 ACS患者PCI术后症状负担可分为3个潜在剖面：低症状负担型（62.8%）、缺血症状主导型（18.4%）和心肺症状主导型（18.8%）。Logistic回归分析显示，年龄（≥65岁）和多支架植入（≥2个）是心肺症状主导型的影响因素（P<0.05），女性是缺血症状主导型的独立影响因素（OR=2.453，P<0.05）。 结论 ACS患者PCI术后症状负担存在明显异质性，临床护理实践中应基于症状剖面特征识别高风险人群，实施分层管理与精准干预。

Objective To identify latent profiles of symptom burden in patients with acute coronary syndrome （ACS） after percutaneous coronary intervention（PCI） and to explore factors associated with different profiles，so as to provide evidence for stratified nursing management. Methods A convenience sampling method was used to recruit 261 patients with ACS who underwent PCI at a tertiary hospital in Chongqing，China，between November 2024 and August 2025. Data were collected using a general information questionnaire，the Cardiac Symptom Survey，and the Seattle Angina Questionnaire. Latent profile analysis was conducted to identify latent classes of symptom burden，and multinomial logistic regression analysis was performed to examine factors associated with different profiles. Results Three latent profiles of symptom burden after PCI were identified，including low symptom burden（62.8%），ischemic symptom dominant type（18.4%），and cardiopulmonary symptom dominant type（18.8%）. Multinomial logistic regression analysis indicated that age（≥65 years） and multiple stent implantation（≥2） were significantly associated with the cardiopulmonary symptom-dominant profile（P<0.05），whereas female was independently associated with the ischemic symptom dominant profile（OR=2.453，P<0.05）. Conclusion Symptom burden after PCI in patients with ACS shows marked heterogeneity. In clinical nursing practice，high-risk patients should be identified based on symptom profile characteristics，and stratified management and targeted interventions should be implemented.