目的 基于潜在剖面分析，探讨急诊科护士变革疲劳的类别特征、类别间差异及其影响因素。方法 于2025年1月—2月，便利抽样选取内蒙古自治区8所三级甲等医院急诊科护士，使用一般资料调查表、变革疲劳量表、组织承诺量表、一般自我效能感量表和心理弹性量表进行调查，通过潜在剖面分析与无序多分类Logistic回归，探究护士变革疲劳的潜在类别特征及其影响因素。结果 共纳入456名急诊科护士，其变革疲劳总分为（26.01±7.38）分。通过潜在剖面分析，将变革疲劳划分为3种类别：低变革疲劳型（26.3%）、中变革疲劳型（55.9%）和高变革疲劳型（17.8%）。分析发现，性别、文化程度、急诊工作年限、组织承诺、自我效能感和心理弹性是影响变革疲劳的主要因素（P<0.05）。结论 急诊科护士的变革疲劳处于中等偏上水平，并呈现不同类别特征。建议护理管理者依据类别特点，采取有针对性的身心干预措施，以缓解其疲劳水平，提升护士应对变革的能力。

Objective Based on the latent profile analysis，the category characteristics，inter-category differences and influencing factors of change fatigue of nurses in emergency department were discussed.Methods From January to February 2025，nurses in the emergency department of eight tertiary hospitals in Inner Mongolia were selected by convenience sampling. The general information questionnaire，the Change Fatigue Scale，the Organizational Commitment Scale，the General Self-efficacy Scale and the Psychological Resilience Scale were used to investigate. Through latent profile analysis and disordered multi-classification Logistic regression，the potential category characteristics and influencing factors of nurses ’ change fatigue were explored.Results A total of 456 emergency nurses were included，and the total score of change fatigue was （26.01±7.38）. Through latent profile analysis，change fatigue was divided into three categories：low fatigue type（26.3%），medium fatigue type（55.9%） and high fatigue type（17.8%）. The analysis found that gender，education level，years of emergency work，organizational commitment，self-efficacy and psychological resilience were the main factors affecting change fatigue（P<0.05）.Conclusion The change fatigue of nurses in the emergency department is above the middle level and presents different types of characteristics. It is suggested that nursing managers should take targeted physical and mental intervention measures according to the characteristics of the categories to alleviate their fatigue level and improve nurses’ ability to cope with changes.