总结经鼻高流量氧疗（high-flownasal cannula，HFNC）在早产儿重度支气管肺发育不良（severe bronchopul-monary dysplasia，sBPD）家庭氧疗中的护理体会。回顾性分析2022年1月—2024年12月收治的6例重度sBPD早产儿HFNC家庭氧疗的临床资料，针对长期依赖家庭氧疗的早产儿sBPD，采取出院前评估及主要照顾者赋能教育，家庭氧疗的实施，根据目标SpO₂确定减停计划，出现呛奶窒息、设备故障等不良事件的正确应对及按计划随访等措施，促进其生长发育，改善家庭生活质量。6例患儿HFNC家庭氧疗期间，1例因呛奶2次、1例因鼻病毒感染再入院外，其余患儿均顺利接受HFNC家庭氧疗。本组1例家庭氧疗130 d时，在吸入氧浓度（fraction of inspired oxygen，FiO₂）降至25%、氧流量10 L/min时直接脱氧；2例分别家庭氧疗268 d、22 d，予序贯至低流量鼻导管吸氧后脱氧；另3例未脱氧患儿按计划随访中。

This study aimed to summarize the nursing experience associated with high-flow nasal cannula （HFNC） oxygen therapy in home oxygen therapy for premature infants diagnosed with severe bronchopulmonary dysplasia（sBPD）. A retrospective analysis was conducted using the clinical data of six preterm infants with sBPD who received HFNC-based home oxygen therapy between January 2022 and December 2024. For preterm infants with long-term dependence on home oxygen therapy，a pre-discharge readiness assessment and caregiver empowerment education were implemented. Key interventions included proper administration of home oxygen therapy，development of discontinuation plans based on target blood oxygen saturation （SpO₂） monitoring，appropriate management of adverse events such as choking，asphyxia，and equipment malfunction，as well as structured follow-up protocols. These measures contributed to improved growth and development outcomes and enhanced family quality of life. During the HFNC home oxygen therapy period，among the six infants，only one required hospitalization twice due to milk aspiration and another was readmitted due to rhinovirus infection；the remaining infants completed therapy without complications. During the HFNC home oxygen therapy of the six infants，one infant choked twice and one was readmitted due to rhinovirus infection，while the rest of the infants received HFNC home oxygen therapy smoothly. Among the three weaned infants，one achieved direct oxygen discontinuation after 130 days of home oxygen therapy when the fraction of inspired oxygen（FiO₂） reached 25% and the oxygen flow rate was maintained at 10 L/min. The other two infants received home oxygen therapy for 268 days and 22 days，respectively，followed by a transition to low-flow nasal cannula oxygen therapy prior to successful oxygen weaning. The other three remain under scheduled follow-up.